Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 29,302 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke. DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain!trillions and trillions of neuronsthatDIEeach day because there areNOeffective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
Saturday, October 29, 2022
Integrin β1 and the Repair after Nervous System Injury
You tell us about the central role of integrin β1 but nothing on how it can be used to recover. Useless.
Integrin β1, as a member of the adhesion molecule family, is widely
distributed in many kinds of cells and participates in multiple
biological functions of the nervous system, including cytoskeleton
reorganization, axon growth, and inflammatory injury.
Summary:
After nervous system injury, integrin β1 expressed by microglia is
mainly involved in promoting inflammatory damage; integrin β1 expressed
by astrocytes plays an important role in axon regeneration; integrin β1
expressed by endothelial cells mainly participates in vascular
remodeling. We concluded that the function of integrin β1 depends on the
location of the receptor cells. The mechanism of integrin β1, which is
involved in the inflammatory response of immune regulatory cells and
affects the axonal regeneration of neuronal cells, is the key to explore
the repair after nervous system injury. The development of drugs
targeting integrin β1 is expected to bring a breakthrough in the
treatment of nervous system injury.
Key Messages:
This
paper expounds the important role of microglia in neurons of the
nervous system and emphasizes the central role of integrin β1 in
regulating non-neuronal cells after nervous system damage.
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