Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, December 5, 2022

Exercise stalled cognitive decline among adults with mild cognitive impairment

It is YOUR DOCTOR'S RESPONSIBILITY to get you recovered enough to do this exercise.

You lost 5 cognitive years from your stroke EXACTLY WHAT PROTOCOLS DOES YOUR DOCTOR HAVE TO RECOVER THAT?

Exercise stalled cognitive decline among adults with mild cognitive impairment

Both moderate aerobic exercise and stretching and balance activities protected against cognitive decline in older adults with mild cognitive impairment, according to research at the Clinical Trials on Alzheimer’s Disease annual meeting.

Laura D. Baker, PhD, professor of gerontology and geriatric medicine at Wake Forest University School of Medicine, and colleagues aimed to test whether 12 months of supervised moderate intensity aerobic exercise protected against cognitive decline compared with low intensity stretching and balancing.

Source: Adobe Stock.
Both high- and low-intensity exercise stalled cognitive decline among older adults with mild cognitive impairment. Source: Adobe Stock

Researchers conducted the EXERT trial at 14 sites and enrolled 296 participants, who were randomized to perform aerobic exercise or stretching, balancing and range-of-motion activities for 18 months. Exercise was supervised during the first 12 months of participation, whereas the last 6 months were unsupervised.

“We tested the effects of physical exercise on cognitive function using a new global composite score, referred to as the ADAS-Cog-Exec,” Baker said during the presentation. “This composite score was developed to be more sensitive to subtle changes in mild cognitive impairment and includes select subtests on the ADAS-Cog-13, additional tests of executive function and select test on the [clinical dementia rating] box scores that are more sensitive to subtle changes in [mild cognitive impairment].”

Study participants were evaluated at baseline and at months 6, 12 and 18. In addition to tests for cognitive function, researchers collected blood for AD biomarker analysis; participants also underwent brain MRI.

For those in the moderate aerobic exercise group, 81% of expected supervised sessions were completed, while those in the low-intensity exercise group completed 87% of sessions. At baseline, participants had mild cognitive impairment (mean Mini-Mental State Examination score = 27.9; mean Clinical Dementia Rating Sum of Boxes = 1.5), and 25% were APOE4 carriers.

“[There was] no difference between the high intensity and low intensity on ADAS-Cog,” Baker said. “Importantly, we also saw no decline. Over time, there was no decline from baseline to month 12 for either group of these amnestic [mild cognitive impairment] individuals.”

According to researchers, the study was the longest exercise trial to date in which mild cognitive impairment was assessed. They acknowledged that the long trial duration, with “greater volume” of exercise, possibly provided more protection, regardless of intensity, and that socialization among participants also may have protected against decline.


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