https://www.mdlinx.com/internal-medicine/medical-news-article/2016/12/14/magnesium-cardiovascular-disease-type-2-diabetes/6975741/?
BMC Medicine, 12/14/2016
For
this study, researchers directed a dose–response meta–analysis of
prospective cohort studies keeping in mind the end goal to research the
relationship between's magnesium consumption and the risk of
cardiovascular disease (CVD), type 2 diabetes (T2D), and all–cause
mortality. Expanding dietary magnesium consumption is connected with a
diminished risk of stroke, heart failure, diabetes, and all–cause
mortality, but not CHD or total CVD. These discoveries bolster the idea
that expanding dietary magnesium may give health benefits.
Methods
- In this study researchers searched PubMed, EMBASE, and Web of Science for articles.
- They searched articles that contained risk estimates for the outcomes of interest and were published through May 31, 2016.
- The pooled results were examined utilizing a random–effects model.
Results
- 40 prospective cohort studies totaling more than 1 million participants were incorporated into the examination.
- Amid the follow–up periods (ranging from 4 to 30 years), 7678 cases of CVD, 6845 cases of coronary heart disease (CHD), 701 cases of heart failure, 14,755 cases of stroke, 26,299 cases of T2D, and 10,983 deaths were reported.
- No significant affiliation was seen between expanding dietary magnesium consumption (per 100 mg/day increment) and the risk of total CVD (RR: 0.99; 95% CI, 0.88–1.10) or CHD (RR: 0.92; 95% CI, 0.85–1.01).
- However, the same incremental increase in magnesium consumption was connected with a 22% diminishment in the risk of heart failure (RR: 0.78; 95% CI, 0.69–0.89) and a 7% reduction in the risk of stroke (RR: 0.93; 95% CI, 0.89–0.97).
- Besides, the outline relative risks of T2D and mortality per 100 mg/day increment in magnesium consumption were 0.81 (95% CI, 0.77–0.86) and 0.90 (95% CI, 0.81–0.99), respectively.
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