Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, September 28, 2019

Can coffee save your life?

I received a new 12 cup coffee maker so I'm now good. The mug I drink out of drains it in three servings, so I need to actually get another 1/2 mug somewhere else.  My reasons for coffee are here: No clue on how much I need for these preventions so I'm not taking any chances on falling short. 























How coffee protects against Parkinson’s Aug. 2014 

 Coffee May Lower Your Risk of Dementia Feb. 2013 

And this: Coffee's Phenylindanes Fight Alzheimer's Plaque  

This also: Two Compounds in Coffee May Team Up to Fight Parkinson's  

The latest here:

Can coffee save your life?

John Murphy, MDLinx | September 23, 2019
Want to live a long and healthy life? Drink a few cups of coffee every day. That’s the gist of a recent meta-analysis published in the European Journal of Epidemiology. People who drink 2 to 4 cups of coffee a day have reduced all-cause mortality and reduced cause-specific mortality compared with people who drink no coffee—even when factors such as age, weight, smoking, and drinking alcohol are taken into account.

Drinking about three to four cups of coffee a day can lower your risk of premature death.
The link between lower mortality and coffee consumption even holds true no matter if it’s decaf or regular.
How much coffee must you drink to get the benefits? The researchers determined that the ideal amount is 3.5 cups of coffee per day to get the greatest risk reduction—15%—in all-cause mortality. For cardiovascular disease (CVD) mortality, 2.5 cups reduce risk the most, by 17%. And 2 cups per day is associated with the lowest relative risk in cancer mortality—4%—compared with drinking no coffee.
You can stop at 3.5 cups a day, though. Drinking more coffee than this won’t increase your longevity any further, the researchers found.(But will the extra prevent dementia and Parkinsons? Inquiring minds need to know.)

Adjusting for other factors

For this analysis, the authors reviewed 40 studies that included a total of 3,852,651 participants. Because they had a large number of studies, the researchers were able to investigate associations between coffee consumption and all-cause mortality for a variety of factors, such as age, sex, geographic region, overweight status, alcohol consumption, and smoking status.
But, it turned out that most of these factors made no difference on coffee’s relation to reduced mortality.
“The inverse association between coffee drinking and all-cause mortality was consistent in various subpopulations by overweight status, alcohol consumption, smoking status and by caffeine content of coffee,” the authors wrote.

What’s in that magic elixir?

Coffee contains more than 1,000 bioactive substances, including caffeine, chlorogenic acids, and diterpenes. But, the researchers speculate that certain antioxidant and anti-inflammatory compounds are the ones responsible for lowering mortality risk.
“Coffee contains various antioxidant components such as caffeine, chlorogenic acid, melanoidins, cafestol, kahweol, and trigonelline,” which may prevent oxidative damage, wrote Youjin Je, ScD, assistant professor, Department of Food and Nutrition, Kyung Hee University, Seoul, South Korea, and co-authors.

“Many human studies also have shown that coffee intake may be associated with the levels of pro-inflammatory biomarkers including tumor necrosis factor-alpha, C-reactive protein, and interleukin 18, and increase the levels of anti-inflammatory biomarkers such as adiponectin,” they added. “These antioxidant and anti-inflammatory properties of coffee compounds may lead to a decreased risk of mortality through slowing the development of some major chronic diseases including diabetes, CVD, and cancers.”
Among those other major diseases, the researchers found that people who drank the most coffee had a 24% lower risk of mortality from diabetes, a 10% lower risk from respiratory disease, and a 35% lower risk from non-CVD, non-cancer causes, compared with people who drank the least amount of coffee.
Mortality risk differed by geographic region, the researchers found. Coffee-drinkers in Europe and Asia had lower risks of mortality than those in the United States.

Closer to conclusive

The authors acknowledged a few limitations to their analysis. For one, the studies they reviewed were observational, so they could not conclude that coffee directly causes reduced mortality. Also, participants self-reported their coffee consumption on questionnaires, which may not be perfectly reliable.
Going forward, Dr. Je and co-authors called for additional, more detailed investigations to further strengthen the link between coffee and reduced mortality.
“Future large prospective studies with detailed information of coffee preparation, sugar and cream added to coffee, or genotype of population could provide a more definitive conclusion on the potential effects of coffee intake on risk of mortality,” they wrote.
This research was supported by the Basic Science Research Program through the National Research Foundation of Korea, and by the Ministry of Science, ICT, and Future Planning.

 

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