Hell, my cognition is great, hasn't helped one bit in my motor recovery. All because you blithering idiots haven't found an EXACT CURE FOR SPASTICITY!
Does a Cognitive Network Contribute to Motor Recovery After Ischemic Stroke?
Abstract
Background
In
stroke patients, preserved cognitive function plays a role in motor
recovery, but there is insufficient evidence on the involved mechanisms.
These mechanisms require investigation in the human brain, which is
composed of large-scale functionally specialized networks.
Objective
In
this study, we investigated the role of cognition-related networks on
upper extremity motor recovery using neuroimaging data of subacute
stroke patients.
Methods
This
study retrospectively analyzed cohort data of 108 subacute ischemic
stroke patients. All patients underwent resting-state functional MRI and
motor function assessments using the Fugl-Meyer assessment (FMA) at
2 weeks after stroke onset. The FMA upper extremity (FMA-UE) score was
obtained again at three months after stroke onset to assess motor
recovery. To construct a resting-state network, cortical surface
parcellation was performed using the Gordon atlas, which included 333
regions of interest, and 12 resting-state networks were extracted.
Linear regression was used to identify the relationships between the
FMA-UE recovery score and resting-state networks.
Results
Cognition-related
networks were correlated with the FMA-UE recovery score, as were
motor-related networks. Interaction effects between motor- and
cognition-related network states existed in motor recovery.
Specifically, cognition-related networks were associated with motor
recovery in patients with a lower strength of motor-related networks.
Conclusions
These
results suggested that the greater the damage to the motor network
caused by stroke is, the more important the cognition-related networks
are in motor recovery.
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