Deans' stroke musings: Association between stroke and Alzheimer's disease: Systematic review and meta-analysis

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Sunday, September 14, 2014

Association between stroke and Alzheimer's disease: Systematic review and meta-analysis

I have been using this study.
Your 33% dementia chance post-stroke from an Australian study
This newest one just says there is a risk but doesn't seem to quantify it.
Regardless, What is your doctor doing to prevent that dementia?
My ideas here;
Dementia prevention 19 ways

Association between stroke and Alzheimer's disease: Systematic review and meta-analysis
The authors conduct a systematic review, to find out the association between stroke and Alzheimer's Disease (AD). These results confirm that AD and intracerebral hemorrhage (ICH) may have common pathogenesis and share preventive treatment measures.
Methods

The authors conducted this systematic review and meta-analysis of stroke on risk for AD and AD on risk for stroke subtypes to clarify the relation between these two disorders on the basis of the studies published from 1975 to November 2013 in the PubMed, EMBASE, and Cochrane Library databases.
In total, 7 cohort studies and 2 nested case-control studies met the inclusion criteria for meta-analysis.
For stroke, the pooled effect size for AD risk was 1.59 (95% CI 1.25–2.02; z=3.76; p=0.000).
For AD dementia, it was not associated with risk of all strokes or ischemic stroke (IS), but the risk of intracerebral hemorrhage (ICH was higher among persons with AD.

Results

The pooled RR for AD in relation to incident IS did not indicate a significant association (RR: 1.13; 95% CI 0.75–1.70; z=0.58; p=0.565).
The pooled effect size for AD and ICH risk was 1.41 (95% CI 1.21–1.66; z=4.27; p<0.001).
Stroke significantly and independently increased risk for AD and in turn AD increased risk for ICH.