Deans' stroke musings: Multivitamin use and risk of stroke mortality

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, May 6, 2015

Multivitamin use and risk of stroke mortality

See what your doctor thinks of this. Or are you just having expensive pee?
http://stroke.ahajournals.org/content/46/5/1167.abstract

The Japan Collaborative Cohort Study

Jia-Yi Dong, MMed;
Hiroyasu Iso, MD, PhD;
Akihiko Kitamura, MD, PhD;
Akiko Tamakoshi, MD, PhD;
Japan Collaborative Cohort Study Group

+ Author Affiliations

From Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine, Osaka, Japan (J.-Y.D., H.I., A.K.); and Department of Public Health, Hokkaido University Graduate School of Medicine, Sapporo, Japan (A.T.).

Correspondence to Hiroyasu Iso, MD, PhD, Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565–0871, Japan. E-mail iso@pbhel.med.osaka-u.ac.jp

Abstract

Background and Purpose—An effect of multivitamin supplement on stroke risk is uncertain. We aimed to examine the association between multivitamin use and risk of death from stroke and its subtypes.

Methods—A total of 72 180 Japanese men and women free from cardiovascular diseases and cancers at baseline in 1988 to 1990 were followed up until December 31, 2009. Lifestyles including multivitamin use were collected using self-administered questionnaires. Cox proportional hazards regression models were used to estimate hazard ratios (HRs) of total stroke and its subtypes in relation to multivitamin use.

Results—During a median follow-up of 19.1 years, we identified 2087 deaths from stroke, including 1148 ischemic strokes and 877 hemorrhagic strokes. After adjustment for potential confounders, multivitamin use was associated with lower but borderline significant risk of death from total stroke (HR, 0.87; 95% confidence interval, 0.76–1.01), primarily ischemic stroke (HR, 0.80; 95% confidence interval, 0.63–1.01), but not hemorrhagic stroke (HR, 0.96; 95% confidence interval, 0.78–1.18). In a subgroup analysis, there was a significant association between multivitamin use and lower risk of mortality from total stroke among people with fruit and vegetable intake <3 times/d (HR, 0.80; 95% confidence interval, 0.65–0.98). That association seemed to be more evident among regular users than casual users. Similar results were found for ischemic stroke.

Conclusions—Multivitamin use, particularly frequent use, was associated with reduced risk of total and ischemic stroke mortality among Japanese people with lower intake of fruits and vegetables.