Since the abstract told me nothing, you'll have to read and decipher the 15 pages at the link yourself.
Effects of Aerobic Training on Brain Plasticity in Patients with Mild Cognitive Impairment: A Systematic Review of Randomized Controlled Trials
s
Farid Farhani 1
, Shahnaz Shahrbanian 1,* , Mohammad Auais 2
, Amir Hossein Ahmadi Hekmatikar 1
and Katsuhiko Suzuki 3,*
1 Department of Sport Science, Faculty of Humanities, Tarbiat Modares University, Tehran P.O. Box 14115-111, Iran;
f.farid1993@yahoo.com (F.F.); a.ahmadihekmatik@modares.ac.ir (A.H.A.H.)
2 Faculty of Health Sciences, School of Rehabilitation Therapy, Queen’s University, Kingston, ON K7L 3N6, Canada;
mohammad.auais@queensu.ca
3 Faculty of Sport Sciences, Waseda University, Tokorozawa 359-1192, Japan
* Correspondence: sh.shahrbanian@modares.ac.ir (S.S.); katsu.suzu@waseda.jp (K.S.);
Tel.: +98(21)82885063 (S.S.); +81-4-2947-6898 (K.S.)
Abstract:
The purpose of this study was to systematically review to find if aerobic exercise compared
to no exercise or any other intervention affects brain plasticity among people with mild cognitive
impairment (MCI). Searches were conducted in the Scopus, SciELO, PubMed, Web of Science, Science
Direct, and Google Scholar databases. The included studies were randomized control trials (RCTs)
written in English comprising individuals with MCI that evaluated the effects of aerobic training on
brain-derived neurotrophic factor (BDNF), brain structures, or brain activity. The quality of trials was
evaluated using the PEDro scale for RCTs. Twelve studies with medium to high quality were included,
of which five studies focused on brain-derived neurotrophic factor (four articles reported elevation
and one article reported no changes in BDNF levels following the aerobic exercise), two studies
focused on brain structures (both reported increases in hippocampus volume following the aerobic
exercise), and five studies focused on brain activity (four articles reported positive changes, and one
article reported no changes in brain activity following the aerobic exercise). Research regarding the
effects of aerobic training on brain plasticity in people with MCI is in its infancy. Still, aerobic exercise
seems to be a promising therapy in people with MCI.
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