http://stroke.ahajournals.org/content/41/10/2157.short
Abstract
Background and Purpose—The purpose of this study was to examine combined effects of hypertension and binge drinking on the risk of mortality from
cardiovascular disease in Koreans.
Methods—This
study followed a cohort of 6100 residents in Kangwha County, aged ≥55
years as of March 1985, for cardiovascular mortality
for 20.8 years up to December 31, 2005. We
calculated hazard ratios (HRs) for cardiovascular mortality by blood
pressure and
binge drinking habits using the Cox proportional
hazard model. Binge drinkers and heavy binge drinkers were defined as
having
≥6 drinks on 1 occasion and ≥12 drinks on 1
occasion.
Results—After
adjusting for total alcohol consumption, male heavy binge drinkers with
Grade 3 hypertension had a 12-fold increased
risk of cardiovascular mortality (HR, 12.7; 95%
CI, 3.47 to 46.5), whereas male binge drinkers with Grade 3 hypertension
had
a 4-fold increased risk of cardiovascular
mortality (HR, 4.41; 95% CI, 1.38 to 14.1) when compared with
nondrinkers with normal
blood pressure. However, in considering separate
effects of heavy binge drinking and hypertension on the risk of
cardiovascular
mortality, HRs were rather low (HR of heavy
binge drinkers, 1.88, 1.10 to 3.20; HR of hypertensives, 2.00, 1.70 to
2.35) compared
with nondrinkers with normal blood pressure.
Conclusions—Binge
drinkers and heavy binge drinkers with Grade 3 hypertension showed a
marked increase in cardiovascular mortality risk.
Even after adjusting for total alcohol
consumption, the former revealed 4.41 and the latter indicated 12.7 of
HR for the risk
of cardiovascular mortality.
I would like to thank for creating this interesting blog and i got a good knowledge to read your informational post, because its having the useful message.
ReplyDelete