https://www.frontiersin.org/articles/10.3389/fneur.2018.00705/full?
- 1Institute of Neuroscience and Physiology, Rehabilitation medicine, University of Gothenburg, Gothenburg, Sweden
- 2Department of Occupational Therapy and Physiotherapy, Sahlgrenska University Hospital, Gothenburg, Sweden
- 3Centre for Person-Centred Care (GPCC), University of Gothenburg, Gothenburg, Sweden
Objective: To investigate the
feasibility of assessing cognitive function using the Montreal Cognitive
Assessment (MoCA) given 36–48 h post stroke to explain dependence in
activities of daily living (ADL).
Methods: This is a cross-sectional,
exploratory study. Cognitive function and basic ADL were assessed with
the MoCA and the Barthel Index (BI), respectively, within 36–48 h of
admission. Neurological functions were assessed with the National
Institute of Health Stroke Scale (NIHSS) upon admittance to the
hospital. Binary logistic regression analyses were performed to assess
the feasibility of the MoCA in explaining ADL dependence.
Results: Data were available for 550 patients (42% females, mean age 69 years). Moderate correlations (rs > +0.30, p
< 0.001) were found between the total score on the BI, MoCA, and
visuospatial/executive functions. The regression analysis model
including only MoCA as an independent variable had a high sensitivity
for explaining ADL dependence. However, the model with independent
variables of MoCA, NIHSS, and age had the best area under the curve
value (0.74).
Conclusions: Cognitive functions
assessed with the MoCA partly explain ADL dependence 36–48 h post
stroke. Stroke-related neurological deficits and age should be
additional considerations.
Introduction
Cognitive functions play an important role in patients' rehabilitation setting management (1)
and safe discharge. Few studies have investigated the utility of
assessing patients' cognitive functions during the early stages of
stroke onset to explain activity-related outcomes. As even mild stroke
can lead to cognitive impairments and influence patients' everyday
functioning (2), it is important to identify these difficulties.
The Montreal Cognitive Assessment (MoCA) is a recommended tool for assessing cognitive functions in patients with acute stroke (3, 4). Good validity and reliability were reported for those with mild to moderate stroke (4).
Studies performed on a subacute stroke population showed a positive
association between impaired cognitive function assessed with the MoCA
and a high level of global disability (5). Poor executive and memory functions were positively associated with dependence in activities of daily living (ADL) (6). However, explanatory factors for favorable ADL outcomes 3 to 12 month post stroke were stroke localization (7), younger age, less severity of neurological deficits, and good function in the upper extremities (7, 8).
The length of stay after the stroke has decreased
substantially and particularly, the patients with very mild to mild
neurological deficits, face very short hospital stay (9).
The clinicians often have only couple of days to identify stroke
related difficulties. Thus, there is increased need of very early
assessments of cognitive functions. The MoCA and basic ADL with the
Barthel Index (BI) are both commonly used instruments for this, in order
to plan discharge. Whether cognitive functions assessed by the MoCA can
explain patients' ADL ability at the early stage of stroke onset
remains unknown. The aim of this study was therefore to investigate the
feasibility of the MoCA to explain ADL dependence 36–48 h post stroke.
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