Deans' stroke musings: Increased risk of stroke observed among patients recovered from COVID-19

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, August 2, 2023

Increased risk of stroke observed among patients recovered from COVID-19

My COVID-19 was mild and now 2 years past I guess I failed to have another stroke.

Increased risk of stroke observed among patients recovered from COVID-19

Patients who recovered from COVID-19 had a higher risk of ischaemic stroke, compared with the general population, within 9 months from the index infection, according to a study published in the European Stroke Journal.

“Data regarding the risk of ischaemic stroke within 1 year after the post-acute

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April W. Armstrong, MD, MPH

1.0 CME / MOC

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phase of COVID-19 remain scant,” wrote Marco Zuin, University of Ferrara, Ferrara, Italy, and colleagues. “We assess the risk of ischaemic stroke in COVID-19 survivors after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by performing a systematic review and meta-analysis of the available data.”

The researchers searched Medline and Scopus to locate all articles published up to February 11, 2023, reporting the risk of incident ischaemic stroke in adult patients who recovered from COVID-19 infection compared with non-infected individuals over the same follow-up period.

Overall, 8 studies involving 23,559,428 patients (mean age 56.1 years; 54.3% males), of whom 1,595,984 had COVID-19, were included in the meta-analysis. All studies were of moderate-high quality according to the Newcastle-Ottawa quality assessment scale.

Over a mean follow-up of 9.2 months, incident ischaemic stroke occurred in 4.40 (95% confidence interval [CI], 4.36-4.43) of 1,000 patients with a previous COVID-19 infection compared with 3.25 (95% CI, 3.21-3.29) of 1,000 non-infected controls.

The analysis showed that patients who recovered from COVID-19 presented a higher risk of ischaemic stroke (hazard ratio [HR] = 2.06; 95% CI, 1.76-2.42; P < .0001; I² = 63.7%) compared with those who did not have COVID-19. Sensitivity analysis confirmed the yielded results with HRs ranging from 1.95 (95% CI, 1.68-2.26; P < .0001; I² = 67.5%) to 2.13 (95% CI, 1.80-2.53; P < .0001; I² = 67.3%), thereby indicating that the obtained results were not driven by any single study.

Further, sub-analysis revealed an increased risk of incident stroke in patients with more severe infection. The risk of stroke was lower in patients who did not require hospitalisation at the time of acute infection (HR = 1.15; 95% CI, 1.01-1.31; I² = 71.4%) compared with those hospitalised (HR = 2.02; 95% CI, 1.16-3.50; I² = 54.5%) and those admitted to intensive care units (HR = 3.65; 95% CI, 2.62-5.10; I² = 51.4%).

“Current data may be useful for minimising the risk of ischaemic stroke events after hospital discharge in COVID-19 survivors, although our results must be considered preliminary and cannot be directly translated into clinical practice giving recommendations regarding the type and regimen of thrombophylactic strategies,” the authors noted. “Further studies are needed to determine the potential benefit of therapeutic anticoagulation for the risk of ischaemic stroke in patients who recovered from COVID-19.”