Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, May 25, 2024

Can personality traits predict dementia?

Conscientiousness - I was extremely this way growing up and through most of my life. I have now decided I will no longer be the responsible person in the group.

For almost all my life, until I moved alone to Michigan, I considered myself introverted. But in order to meet people here I jumped at any invitation.  

Positive affectivity refers to positive emotions and expression, including cheerfulness, pride, enthusiasm, energy, and joy. This describes me pretty well. Life is great.

Ask your competent? doctor if these traits are enough to prevent your risk of dementia post stroke.

Your risk of dementia, has your doctor told you of this?

1. A documented 33% dementia chance post-stroke from an Australian study?   May 2012.

2. Then this study came out and seems to have a range from 17-66%. December 2013.`    

3. A 20% chance in this research.   July 2013.

4. Dementia Risk Doubled in Patients Following Stroke September 2018

The latest here:

 

Can personality traits predict dementia?

An NIA-funded study supports a predictive link between personality traits and dementia. The study found that conscientiousness, extraversion, and positive affect were associated with a lower risk for dementia while neuroticism and negative affect were associated with an increased risk. However, no associations were found between personality traits and dementia-related brain changes. The results, published in Alzheimer’s and Dementia, the Journal of the Alzheimer’s Association, may help researchers understand whether changes in personality can predict one’s risk for dementia.senior-beautiful-grey-haired-woman-wearing-casual-shirt-and-glasses-over-yellow

For this study, researchers from Northwestern University and the University of California, Davis analyzed data from 44,531 participants who were part of eight separate longitudinal studies conducted in three continents and five countries. The team harmonized the data and tested whether personality traits and subjective reports of well-being predicted neuropsychological and neuropathological characteristics of dementia.

The results support the idea that certain personality traits may be risk factors for dementia. Neuroticism, low conscientiousness, and negative affect were associated with dementia diagnoses across samples, measures, and time. Other personality traits may be more protective; for example, conscientiousness, extraversion, and positive affect were associated with a lower risk for dementia.

Among the combined participant data, approximately 50% of all the cases included autopsies. A limited number of samples (1,703) from the combined data were from people who developed dementia. This enabled researchers to compare autopsy results with personality traits. They found no consistent associations. One limitation of the study is that all the neuropathology samples were from the United States and none of the studies were representative with respect to race.

The study authors note that more research is needed to prospectively explore such associations using biomarkers of dementia and among more diverse and inclusive populations and to establish whether aspects of personality or subjective well-being are causally linked to dementia outcomes.

This research was supported by NIA grants P01AG043362, R01AG018436, R01AG067622, R01AG017917, P30AG010161, P30AG72975, R01AG15819, R01AG072559, and P01AG03949.

These activities relate to NIH’s AD+ADRD Research Implementation Milestones 2.J, Disease Mechanisms: Social and psychosocial factors, and 11.B, Enabling Tech: Outcome measures harmonization.

Reference: Beck ED, et al. Personality predictors of dementia diagnosis and neuropathological burden: An individual participant data meta-analysis. Alzheimer’s & Dementia. 2024;20(3):1497-1514. doi: 10.1002/alz.13523.

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