Deans' stroke musings: Cut stroke in half: Polypill for primary prevention in stroke

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, May 27, 2024

Cut stroke in half: Polypill for primary prevention in stroke

This still leaves 5 million persons a year disabled by stroke! Which is why the WSO needs to be run by survivors, they wouldn't leave anyone behind because they would solve stroke to 100% recovery! LEADERS SOLVE PROBLEMS; nobody in the WSO is a leader!

Cut stroke in half: Polypill for primary prevention in stroke

Michael Brainin¹, Valery Feigin², Sheila Martins³, Karl Matz⁴, Jayanta Roy⁵, Peter Sandercock⁶, Yvonne Teuschl¹, Jaakko Tuomilehto^{7

8

9}, Anita Wiseman¹⁰

Affiliations

PMID: 29461155
DOI: 10.1177/1747493018761190

Abstract

The study was designed to prove the World Stroke Organisation’s concept of a
comprehensive intervention approach in primary prevention to “Cut Stroke in Half”,
conceived by former World Stroke Organisation President Michael Brainin from Austria,
and Professor Valery Feigin from New Zealand.

This review summarizes the potential for polypill therapies for stroke prevention. While a number of studies applying different approaches regarding polypill have been performed, none of them has had a focus on stroke as the main outcome. A combination pill containing drugs such as statins, diuretics, and other antihypertensives is currently available in various formats. Estimates focusing mostly on primary prevention show that using such a combination drug a reduction in the 5-year stroke incidence by 50% can be achieved - especially in low- and middle-income countries with a high prevalence of risk factors even among people at young ages. A combination of a large supporting population-wide program with a registry-based quality control is the most likely perspective and can be achieved within a reasonable time frame and potentially have significant influence in young stroke populations.