Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, August 28, 2013

Thinking with your gonads: testosterone and cognition

A question for your doctor. Is testosterone deprivation the cause of your memory and cognition problems? Because you lowered your cholesterol?
http://www.sciencedirect.com/science/article/pii/S1364661305003578
  • Department of Behavioral Neuroscience, Oregon Health & Science University CR131, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA

Sex hormones play a crucial role during brain development, but do they modulate or maintain cognition throughout life? Despite several million prescriptions annually for testosterone supplementation, we do not really know the answer. Here I review recent evidence that testosterone alters neural activity essential for learning and memory, and plays an important role as a neuroprotective agent in aging. In particular, testosterone deprivation is associated with poor memory in men and replacement can enhance memory and spatial cognition. However, there is little evidence that testosterone selectively affects only those cognitive domains where sex differences in performance have been found. There are also gaps in our knowledge surrounding the individual cognitive processes altered by testosterone, their neural basis, and the degree to which testosterone affects cognitive performance in women.
 This figure from the abstract bings up even more questions for your doctor. How does cholesterol lowering drugs affect your testosterone levels and cognition?

Full-size image (19 K)Figure 2. Testosterone is a hormone that is metabolized from cholesterol. Thus, its production can be influenced at several metabolic steps. In addition, it can be further metabolized to form estradiol or other androgen molecules. When testosterone affects cognition, it is not known in most instances whether this is as an androgen or via its conversion to estradiol.

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