Deans' stroke musings: Regional Low Cerebral Blood Flow Predicts Leukoaraiosis Development at 18 Months in Patients with TIA and Minor Stroke

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, August 26, 2013

Regional Low Cerebral Blood Flow Predicts Leukoaraiosis Development at 18 Months in Patients with TIA and Minor Stroke

What is your doctor doing to identify this and prevent its occurrence? ANYTHING AT ALL?
Shouldn't your doctor know more than this graduate student?
http://theses.ucalgary.ca/handle/11023/884

Author:	Bernbaum, Manya
Supervisor:	Coutts, Shelagh
Submission Date:	2013
Institution:	University of Calgary
Faculty:	Graduate Studies
Graduate Program:	Medicine, Neuroscience
URI:	http://hdl.handle.net/11023/884
Subject Area:	Neuroscience
Keywords:	Minor Stroke Leukoaraiosis Cerebral Blood Flow TIA MR Perfusion White Matter Disease White Matter Hyperintensity
Type:	Thesis
Degree:	MSc
Abstract:	The purpose of this study was to investigate whether low cerebral blood flow (CBF) is associated with subsequent white matter hyperintensity (WMH) development in minor stroke and transient ischemic attack (TIA) patients. New WMH at 18 months were identified by comparing follow-up with baseline FLAIR, and regions of interest (ROI) were placed in normal appearing and hyperintense white matter. Co-registered CBF maps were used to quantify relative CBF. Forty patients were evaluated, where mean age was 62+/-12 years, 78% male and 9% diabetic. A mixed effects logistic regression accounting for “within patient” clustering, showed that as CBF increases by 1mL/100g/min, the odds of having a new WMH decrease by 0.61. Results suggest that regions of white matter that develop WMH at 18 months have low baseline CBF. Future studies aiming to improve cerebral perfusion in normal appearing white matter might provide a target for arresting the development of WMH.