Deans' stroke musings: Risk of ischemic stroke associated with calcium supplements with or without vitamin D: A nested case-control study

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, June 2, 2017

Risk of ischemic stroke associated with calcium supplements with or without vitamin D: A nested case-control study

Be careful out there, read the whole thing.
https://www.mdlinx.com/internal-medicine/medical-news-article/2017/06/02/calciumstrokevitamin-d/7196063/?

June 02, 2017

Recent Journal Summaries #2 of 140

Risk of ischemic stroke associated with calcium supplements with or without vitamin D: A nested case-control study

Journal of the American Heart Association

de Abajo FJ, et al. – This study was designed to shed light on the association between ischemic stroke and use of calcium supplements either in monotherapy or in combination with vitamin D. Findings indicated an amplification in the risk of ischemic stroke consequent to the administration of high doses of calcium supplement monotherapy, whereas calcium supplementation with vitamin D seemed to offset this hazard.

Methods

Researchers performed a nested case-control study with patients aged 40 to 89 years old, among whom a total of 2690 patients had a first episode of nonfatal ischemic stroke and for which 19 538 controls were randomly selected from the source population and frequency-matched with cases for age, sex, and calendar year.
Logistic regression provided the odds ratios while adjusting for confounding factors.
Furthermore, they performed a sensitivity analysis by restricting to patients who were new users of calcium supplements as either monotherapy or with vitamin D.

Results

Findings demonstrated that calcium supplementation with vitamin D was not associated with an increased risk of ischemic stroke (odds ratio 0.85; 95% confidence interval, 0.67–1.08) in the population as a whole or under any of the conditions examined (dose, duration, background cardiovascular risk, sex, or age).
Researchers also observed that calcium supplement monotherapy was not associated with an increased risk in the population as a whole (odds ratio 1.18; 95% confidence interval, 0.86–1.61), although a significant increased risk at high doses (≥1000 mg/day: odds ratio 2.09; 95% confidence interval, 1.25–3.49; <1000 mg: odds ratio 0.76; 95% confidence interval, 0.45–1.26) compared with nonuse was observed.
Data also revealed that the sensitivity analysis did not affect the inferences, with similar results observed among new users as to the overall study population.