Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Thursday, August 23, 2012

Supersmall lab-on-a-chip is superfast

This really seems like some excellent technology to prove what type of stroke you had. And if we are going to continue down the tPA route then we had better get a faster, less technology intensive and less education needed way of determining the type of stroke you had.
http://www.sciencenews.org/view/generic/id/343100/title/Supersmall_lab-on-a-chip_is_superfast
Looking for a specific protein in a drop of blood is like trying to find a notorious white whale on the seven seas — it takes some time. But a new device quickly filters the ocean of molecules in a blood sample, capturing proteins that may warn of an impending heart attack or out-of-whack insulin levels. Besides detecting potential emergencies, such devices could minimize the fraught days a patient spends waiting for lab results, providing them in mere minutes.
http://www.genomeweb.com//node/1119771?hq_e=el&
Researchers from Tel Aviv University in Israel have developed a nanowire-based device to separate and analyze protein biomarkers in blood samples. As they report in Nano Letters, the filtering, separation, and analysis all occurs on a single chip — and rapidly. The chip, adds ScienceNews, is made of two compartments, one that is full of a "forest" of densely packed nanowires coated with protein-specific antibodies and one that contains flat nanowires, also coated with antibodies, that are connected to electrodes. The researchers tested their device on its ability to detect troponin T, which it was able to do sensitively and in less than 10 minutes. "It's clever," Yale University's Tarek Fahmy tells ScienceNews. "They are doing separation and concentration on the same chip." 
http://pubs.acs.org/doi/abs/10.1021/nl3021889
Importantly, this is the first demonstration of an all-NWs device for the whole direct analysis of blood samples on a single chip, able to selectively collect and separate specific low abundant proteins, while easily removing unwanted blood components (proteins, cells) and achieving desalting effects, without the requirement of time-consuming centrifugation steps, the use of desalting or affinity columns.

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