Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, April 2, 2014

Effects of Noninvasive Facial Nerve Stimulation in the Dog Middle Cerebral Artery Occlusion Model of Ischemic Stroke

This has got to be one of the easiest stroke protocols to implement. It validates the rat whisker tickling. How stupid do our stroke hospitals have to be to not implement this in the next week?
What the hell is the downside of doing this? I'm sure you could get informed consent from any relative.  
GAH!!! I bet on 30 years.
http://stroke.ahajournals.org/content/early/2014/02/18/STROKEAHA.113.003243.abstract
  1. Emilio Sacristan, PhD
+ Author Affiliations
  1. From Northern Neurosciences Inc, Orinda, CA (M.K.B., C.Y., D.B., T.H.); Nervive Inc, Akron, OH (M.K.B., E.S.); Department of Pathology, University of Michigan, Ann Arbor, MI (C.Y.); Wayne State University, Detroit, MI (D.B.); Department of Neurosurgery, Hospital Central Norte-PEMEX, Mexico City, Mexico (F.C.P.); and National Center for Medical Imaging and Instrumentation Research (CI3M), Universidad Autónoma Metropolitana-Iztapalapa, Mexico City, Mexico (A.G., J.A., E.S.).
  1. Correspondence to Mark K. Borsody, MD, PhD, Nervive Inc, 526 S. Main St, Akron, OH 44311. E-mail mborsody@nervive.com

Abstract

Background and Purpose—Facial nerve stimulation has been proposed as a new treatment of ischemic stroke because autonomic components of the nerve dilate cerebral arteries and increase cerebral blood flow when activated. A noninvasive facial nerve stimulator device based on pulsed magnetic stimulation was tested in a dog middle cerebral artery occlusion model.
Methods—We used an ischemic stroke dog model involving injection of autologous blood clot into the internal carotid artery that reliably embolizes to the middle cerebral artery. Thirty minutes after middle cerebral artery occlusion, the geniculate ganglion region of the facial nerve was stimulated for 5 minutes. Brain perfusion was measured using gadolinium-enhanced contrast MRI, and ATP and total phosphate levels were measured using 31P spectroscopy. Separately, a dog model of brain hemorrhage involving puncture of the intracranial internal carotid artery served as an initial examination of facial nerve stimulation safety.
Results—Facial nerve stimulation caused a significant improvement in perfusion in the hemisphere affected by ischemic stroke and a reduction in ischemic core volume in comparison to sham stimulation control. The ATP/total phosphate ratio showed a large decrease poststroke in the control group versus a normal level in the stimulation group. The same stimulation administered to dogs with brain hemorrhage did not cause hematoma enlargement.
Conclusions—These results support the development and evaluation of a noninvasive facial nerve stimulator device as a treatment of ischemic stroke.

1 comment:

  1. I'm going to try pinching my cheeks the way my grandmother did to see if I feel more alert.

    ReplyDelete