What the hell is the downside of doing this? I'm sure you could get informed consent from any relative.
GAH!!! I bet on 30 years.
http://stroke.ahajournals.org/content/early/2014/02/18/STROKEAHA.113.003243.abstract
- Mark K. Borsody, MD, PhD,
- Chisa Yamada, MD,
- Dawn Bielawski, PhD,
- Tamara Heaton, MA,
- Fernando Castro Prado, MD,
- Andrea Garcia, MS,
- Joaquín Azpiroz, PhD and
- Emilio Sacristan, PhD
+ Author Affiliations
- Correspondence to Mark K. Borsody, MD, PhD, Nervive Inc, 526 S. Main St, Akron, OH 44311. E-mail mborsody@nervive.com
Abstract
Background and Purpose—Facial
nerve stimulation has been proposed as a new treatment of ischemic
stroke because autonomic components of the nerve
dilate cerebral arteries and increase
cerebral blood flow when activated. A noninvasive facial nerve
stimulator device based
on pulsed magnetic stimulation was tested in a
dog middle cerebral artery occlusion model.
Methods—We used an
ischemic stroke dog model involving injection of autologous blood clot
into the internal carotid artery that reliably
embolizes to the middle cerebral artery.
Thirty minutes after middle cerebral artery occlusion, the geniculate
ganglion region
of the facial nerve was stimulated for 5
minutes. Brain perfusion was measured using gadolinium-enhanced contrast
MRI, and
ATP and total phosphate levels were measured
using 31P spectroscopy. Separately, a dog model of brain hemorrhage involving puncture of the intracranial internal carotid artery
served as an initial examination of facial nerve stimulation safety.
Results—Facial
nerve stimulation caused a significant improvement in perfusion in the
hemisphere affected by ischemic stroke and a
reduction in ischemic core volume in
comparison to sham stimulation control. The ATP/total phosphate ratio
showed a large
decrease poststroke in the control group
versus a normal level in the stimulation group. The same stimulation
administered
to dogs with brain hemorrhage did not cause
hematoma enlargement.
Conclusions—These results support the development and evaluation of a noninvasive facial nerve stimulator device as a treatment of ischemic
stroke.
I'm going to try pinching my cheeks the way my grandmother did to see if I feel more alert.
ReplyDelete