Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:

Thursday, August 11, 2016

Environmental enrichment as an intervention for adverse health outcomes of prenatal stress

Should be able to be applied to the stress and resiliency needed from your stroke.
I know if you read Jill Bolte-Taylors' book or saw her on video, she highly recommended not having much sensory stimulation at all because it caused her to shut down. To each his or her own,

DOI: dvw013 First published online: 6 August 2016


Prenatal stress (PS) has complex neurological, behavioural and physiological consequences for the developing offspring. The phenotype linked to PS usually lasts into adulthood and may even propagate to subsequent generations. The often uncontrollable exposure to maternal stress and the lasting consequences emphasize the urgent need for treatment strategies that effectively reverse stress programming. Exposure to complex beneficial experiences, such as environmental enrichment (EE), is one of the most powerful therapies to promote neuroplasticity and behavioural performance at any time in life. A small number of studies have previously used EE to postnatally treat consequences of PS in the attempt to reverse deficits that were primarily induced in utero. This review discusses the available data on postnatal EE exposure in prenatally stressed individuals. The goal is to determine if EE is a suitable treatment option that reverses adverse consequences of stress programming and enhances stress resiliency. Moreover, this review discusses data with respect to relevant hypotheses including the cumulative stress and the mismatch hypotheses. The articles included in this review emphasize that EE reverses most behavioural, physiological and neural deficits associated with PS. Differing responses may be dependent on the timing and variability of stress and EE, exercise, and potentially vulnerable and resilient phenotypes of PS. Results from this study suggest that enrichment may provide an effective therapy for clinical populations suffering from the effects of PS or early life trauma.
  • maternal stress
  • pregnancy
  • enriched environment
  • mismatch hypothesis
  • hypothalamic–pituitary–adrenal axis
  • HPA axis
  • stress response
  • stress vulnerability
  • stress resilience
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (, which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact
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