Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Sunday, March 11, 2018

The Role of Diaschisis in Stroke Recovery

A new word I learned from Peter Levine, although in this case it is considered useful.  Hopefully your doctor is using this for your recovery, it has only been around for 17+ years.
http://stroke.ahajournals.org/content/30/9/1844.short
Rüdiger J. Seitz, Nina P. Azari, Uwe Knorr, Ferdinand Binkofski, Hans Herzog, Hans-Joachim Freund
Download PDF
https://doi.org/10.1161/01.STR.30.9.1844
Stroke. 1999;30:1844-1850
Originally published September 1, 1999

Abstract

Background and Purpose—Recovery from hemiparesis after stroke has been shown to involve reorganization in motor and premotor cortical areas. However, whether poststroke recovery also depends on changes in remote brain structures, ie, diaschisis, is as yet unresolved. To address this question, we studied regional cerebral blood flow in 7 patients (mean±SD age, 54±8 years) after their first hemiparetic stroke.
Methods—We analyzed imaging data voxel by voxel using a principal component analysis by which coherent changes in functional networks could be disclosed. Performance was assessed by a motor score and by the finger movement rate during the regional cerebral blood flow measurements.
Results—The patients had recovered (P<0.001) from severe hemiparesis after on average 6 months and were able to perform sequential finger movements with the recovered hand. Regional cerebral blood flow at rest differentiated patients and controls (P<0.05) by a network that was affected by the stroke lesion. During blindfolded performance of sequential finger movements, patients were differentiated from controls (P&ly;0.05) by a recovery-related network and a movement-control network. These networks were spatially incongruent, involving motor, sensory, and visual cortex of both cerebral hemispheres, the basal ganglia, thalamus, and cerebellum. The lesion-affected and recovery-related networks overlapped in the contralesional thalamus and extrastriate occipital cortex.
Conclusions—Motor recovery after hemiparetic brain infarction is subserved by brain structures in locations remote from the stroke lesion. The topographic overlap of the lesion-affected and recovery-related networks suggests that diaschisis may play a critical role in stroke recovery.
  • Received February 2, 1999.
  • Revision received May 10, 1999.
  • Accepted June 4, 1999.
View Full Text
Posted by at
Labels: ,

1 comment:

  1. JadeMarch 28, 2018 at 4:53 PM

    I've been fascinated by the role of diaschisis since my partner's aneurysm + 5 ischemic strokes nearly two years ago. It's incredible to me that more research isn't being done to determine the part it plays in predicting recovery outcome, although, I think it must be huge, as my partner is doing literally hundreds of things his idiot doctors wrote off as impossible at the time of his initial scans.

    ReplyDelete

Subscribe to: Post Comments (Atom)