Pretty much useless without a protocol. And your doctor and stroke hospital will do nothing to get to a protocol.
Do we follow this Spaniard and use red wine? He does have an amount, three liters a day.
Man Dies Aged 107, Thanked Red Wine For Long Life - 3 liters a day, no water
Will follow in this Spaniard's footsteps. Don't listen to me, not medically trained.
The latest here:
Can this simple dietary change save your brain?
John James|May 27, 2020
Dementia
mostly affects senior citizens, but it’s a major public health
challenge for everyone. Ten million new cases are reported each year,
with the global cost of care expected to reach $2 trillion by 2030.
While there’s no cure or surefire treatment to slow the progression of
dementia, new research suggests that a change in diet could help stave
off its effects.
Flavonoids in foods can protect the brain from dementia.
Recent
findings indicate that flavonoids, which are among the most abundant
micronutrients present in plant foods, play a powerful role in
protecting the brain from dementia. Common dietary sources of flavonoids
include citrus fruits, apples, berries, onions, soybeans, legumes—and even chocolate and wine. A growing body of evidence
suggests that these natural substances interact with the components of
the brain that control memory. But there’s no consensus on how
beneficial these plant compounds are, or whether it’s possible to
actually consume too many flavonoids.
Brain benefits from flavonoids
Flavonoids
are considered a key component in pharmaceutical and medicinal
applications because of their known antioxidative, anti-inflammatory,
antimutagenic, and anticarcinogenic properties. The most recent data
on different plant metabolites suggests that flavonoids interact with
receptor systems of the brain, stimulating neuronal regeneration,
scavenging free radicals, and preventing neuronal dysfunction.
A recent study published in The American Journal of Clinical Nutrition
examined the relationship between dietary flavonoid intake and the risk
of Alzheimer disease and related dementias (ADRD). The study used
participant data from the Framingham Heart Study, which documented the
chronic disease risk factors of 5,000 adults over 2 decades. Of the
2,800 participants who qualified for the latest study, all completed
dietary assessments over the course of a year.
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Results
indicated that individuals with the highest intakes of flavonoids had a
lower risk of ADRD vs individuals with the lowest flavonoid intakes.
The
authors concluded: “Our findings imply that higher long-term dietary
intakes of flavonoids are associated with lower risks of ADRD and AD in
US adults.”
These findings support an earlier study
that analyzed the dietary intake of participants in the Nurses’ Health
Study—one of the largest ongoing investigations into the risk factors
for major chronic diseases in women. After measuring the cognitive
function of 16,000 participants, the researchers concluded that greater
intakes of blueberries and strawberries—high-flavonoid foods—were
associated with slower rates of cognitive decline.
Body benefits from flavonoids
Epidemiological studies have also reported that flavonoid-rich diets are associated with a reduced risk of cardiovascular diseases, diabetes, and some types of cancers.
For example, researchers followed the health and diet of 56,000 Danish
adults for 23 years to investigate the correlation between flavonoid
intake and heart disease and cancer. The study, published in Nature Communications,
confirmed that a moderate habitual intake of flavonoids is inversely
correlated with all-cause, cardiovascular disease-related, and
cancer-related mortality. Notably, these associations plateaued at
flavonoid intakes of 500 mg a day.
“The
strongest associations observed between flavonoids and mortality was in
smokers and high alcohol consumers, with higher intakes being more
beneficial,” the authors wrote. “These findings highlight the potential
to improve population health through dietary recommendations to ensure
adequate consumption of flavonoid-rich foods, particularly in these
high-risk populations.”
The idea that
flavonoid consumption leads to greater health overall is well supported,
both in scientific literature and popular culture. For instance,
flavonoid-rich foods are staples of the Mediterranean diet, a way of eating that focuses on fruits, vegetables, and whole grains. The Mediterranean diet is not only consistently ranked the best diet overall by U.S. News & World Report, but is also linked to better cognitive function and lower risk of cognitive decline in older adults.
Are flavonoids all they’re cracked up to be?
Although
the research bends strongly in favor of flavonoids, some findings
recommend being careful about how often you ingest these plant
compounds. Existing research notes that the potential toxic effects of
excessive flavonoid intake have been understudied.
An
analysis of the health impacts of flavonoids suggests that the
compounds can act as mutagens at higher doses, which means they generate
free radicals and inhibit key enzymes involved in hormone metabolism.
“Thus,
in high doses, the adverse effects of flavonoids may outweigh their
beneficial ones, and caution should be exercised in ingesting them at
levels above that which would be obtained from a typical vegetarian
diet,” the authors wrote. “This suggests that unregulated, commercially
available flavonoid-containing supplements may have biologic activity
that can adversely affect human health.”
In
addition, flavonoids have the potential to interact with prescription
drugs. A flavonoid found in grapefruit, for example, has been identified
as interfering with medications such as calcium channel blockers,
immunosuppressants, and antihistamines—inhibiting their potency.
Flavonoids can help fight dementia
While
researchers agree that there is still much to learn about flavonoids,
including determining their optimal level of consumption, it’s clear
that a flavonoid-rich diet is beneficial for the body and brain. As
research advances, more will be known about the specific interactions of
flavonoids and cognitive function, but until then there is an added
advantage to increasing the fruits and vegetables in your diet:
investing in your health and mind.
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