Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, May 21, 2020

Tiny implanted sensors monitor brain injuries, then dissolve away

You'll have to ask your doctor and stroke hospital if this ever made it to human testing. Because with just a few modifications with nanosensors we could listen in on individual neuron signals and figure out EXACTLY what happens during neuroplasticity.  Assuming of course that there is anyone in stroke research that has two neurons to rub together for a spark of innovation.

 

Tiny implanted sensors monitor brain injuries, then dissolve away


A tiny implantable brain sensor could someday monitor conditions within the skull before dissolving away. Currently being tested in rats, this technology tracks temperature and pressure levels, potentially offering a new option for how brain injuries are studied and treated. By melting away when no longer useful, these micro-sized sensors remove the risks associated with current technology used to monitor brain injuries, according to a University of Illinois press release.
The study, led by John A. Rogers, professor of material sciences and engineering at the University of Illinois at Urbana-Champaign, and Wilson Ray, professor of neurological surgery at the Washington University School of Medicine in St. Louis, is published in the journal Nature.
"This is a new class of electronic biomedical implants," Rogers said in the release. "These kinds of systems have potential across a range of clinical practices, where therapeutic or monitoring devices are implanted or ingested, perform a sophisticated function, and then resorb harmlessly into the body after their function is no longer necessary."
Rogers stressed that the technology now used for monitoring after traumatic brain injuries or brain surgery can be dangerous for patients. Systems involve bulky wires that restrict patients' movements, and invasive implants may lead to brain hemorrhages, allergic reactions, and infections.
By contrast, the tiny dissolvable silicon devices that Rogers' team developed are smaller than a grain of rice. They are naturally biodegradable -- built up on incredibly thin silicon sheets -- and dissolve away after a few weeks of monitoring brain activity. They melt harmlessly into the human body's own fluids, the researchers say.
These devices are sensitive to pressure levels in the intracranial fluid that surrounds the brain, and have a temperature sensor synced to a wireless postage stamp-sized transmitter that is placed on top of the skull.
sensor-transmitter.jpg
The small sensor connects to an embeddable wireless transmitter that lies on top of the skull. Courtesy of John A. Rogers
"If you simply could throw out all the conventional hardware and replace it with very tiny, fully implantable sensors capable of the same function, constructed out of bioresorbable materials in a way that also eliminates or greatly miniaturizes the wires, then you could remove a lot of the risk and achieve better patient outcomes," Rogers added. "We were able to demonstrate all of these key features in animal models, with a measurement precision that's just as good as that of conventional devices."
The lab tests with rats were to see how compatible these tiny devices would be with a living organism's body.
So, what's the next phase? The team hopes to move toward human trials soon.
"The ultimate strategy is to have a device that you can place in the brain -- or in other organs in the body -- that is entirely implanted, intimately connected with the organ you want to monitor and can transmit signals wirelessly to provide information on the health of that organ, allowing doctors to intervene if necessary to prevent bigger problems," Rory Murphy, a neurosurgeon at Washington University who was a co-author of the paper.


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