It seems I've been missing a lot of studies on this, so ask your doctor the status of all this research. You do expect your doctor to be up-to-date on stroke research? Otherwise you would be selecting a better doctor, right?
Nitric oxide mechanism in the protective effect of naringin against post-stroke depression (PSD) in mice 2010
Preventive effects of hesperidin, glucosyl hesperidin and naringin on hypertension and cerebral thrombosis in stroke‐prone spontaneously hypertensive rats 2012
Therapeutic potential of naringin in neurological disorders 2019
Naringin reverses neurobehavioral and biochemical alterations in intracerebroventricular collagenase-induced intracerebral hemorrhage in rats 2017
The beneficial role of Naringin-a citrus bioflavonoid, against oxidative stress-induced neurobehavioral disorders and cognitive dysfunction in rodents: A systematic … 2017
Protective effect of naringin against ischemic reperfusion cerebral injury: possible neurobehavioral, biochemical and cellular alterations in rat brain 2009
Naringin attenuates cerebral ischemia-reperfusion injury through inhibiting peroxynitrite-mediated mitophagy activation 2018
The effect of ozone and naringin on intestinal ischemia/reperfusion injury in an experimental model 2015
Preclinical evidence for the pharmacological actions of naringin: a review 2014
And that's just the first page of 'naringin and stroke' in Google Scholar.
The latest here:
Therapeutic potential of naringin: an overview
Abstract
Context: Naringin is a natural flavanone glycoside that is found in the Chinese herbal medicines and citrus fruits. Studies have demonstrated that naringin possesses numerous biological and pharmacological properties, but few reviews of these studies have been performed.
Objective: The present review gathers the fragmented information available in the literature describing the extraction of naringin, its pharmacology and its controlled release formulations. Current research progress and the therapeutic potential of naringin are also discussed.
Methods: A literature survey for relevant information regarding the biological and pharmacological properties of naringin was conducted using Pubmed, Sciencedirect, MEDLINE, Springerlink and Google Scholar electronic databases from the year 2007–2015.
Results: Naringin modulates signalling pathways and interacts with signalling molecules and thus has a wide range of pharmacological activities, including anti-inflammatory, anti-cancer activities, as well as effects on bone regeneration, metabolic syndrome, oxidative stress, genetic damage and central nervous system (CNS) diseases. Information was gathered that showed the extraction of naringin can be improved using several modifications. There has been some progress in the development of controlled release formulations of naringin.
Conclusion: Naringin is a promising candidate for further in vivo studies and clinical use. More detailed studies regarding its mechanism of action are required.
Introduction
Naringin (Figure 1), a flavanone glycoside that is formed from the flavanone naringenin and the disaccharide neohesperidose, is one of the main active components of Chinese herbal medicines, such as Drynaria fortunei (Kunze) J. Sm. (DF), Citrus aurantium L. (CA) and Citrus medica L. (CM) (Zhang et al. 2014; Yin et al. 2015b;). It is also present in citrus fruits (Wong et al. 2013) and imparts a bitter taste to citrus juices (Chtourou et al. 2015).
Flavonoids are an important group of secondary metabolites and a source of bioactive compounds in plants (Ghasemzadeh & Jaafar 2013). An extensive literature survey has revealed that naringin possesses antioxidant, anti-inflammatory, anti-apoptotic, anti-ulcer, anti-osteoporotic and anti-carcinogenic properties (Wang et al. 2013). However, there have been few reports, until recently, which describe naringin processing.
A relatively simple and high-yield method for the extraction and purification of naringin that is applicable to agricultural wastes such as citrus fruit peels, has recently been described (Kanokorn et al. 2009). Controlled release formulations of naringin could reduce the total dose of medication required (Kim & Tabata 2015), and these formulations should have high encapsulation efficiencies and stable drug release behaviours (Cordenonsi et al. 2015). Controlled release formulations of naringin have been shown to affect bone regeneration and to potentially promote bone healing (Chen et al. 2013).
The present review focuses on current studies describing the in vivo and in vitro effects of naringin, highlighting the potential value of this compound and the diversity of its pharmacological activities.
More at link.
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