Extended-Window Thrombolysis Improves Stroke Outcomes with increased bleeding risk: JAMA

 Will your competent? doctor and hospital ENSURE FURTHER RESEARCH OCCURS that will determine the best way to prevent the bleeding risk? Oh NO; the plan is TO DO NOTHING!  Everyone there needs to be fired! I take no prisoners in trying to get stroke solved!

Extended-Window Thrombolysis Improves Stroke Outcomes with increased bleeding risk: JAMA

Nigerian Innovator Develops Robotic Rehabilitation Glove For Stroke Survivors

 Ask your competent? doctor if spastic fingers can get in these.

Have your competent? doctor validate that this is better than all these other ones out there. Can't do that? PURE INCOMPETENCE! I take no prisoners in getting stroke solved to 100% recovery. Aren't even trying to get there, then REMOVE THAT DEAD WOOD!

Gyroscopic glove (1)

HERO Grip Glove (1)

music glove (1)

RAPAEL Smart Glove (5)

SaeboGlove (1)

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EsoGlove (4) 

ExoGlove (1)

glove (109 posts)

Nigerian Innovator Develops Robotic Rehabilitation Glove For Stroke Survivors

Ascension Sacred Heart Emerald Coast celebrates Primary Stroke certification and honors care teams

 Primary Stroke certification doesn't guarantee recovery so this hospital is still a failure! I take no prisoners in trying to get stroke solved and that means stomping on lots of entitled toes!

Ascension Sacred Heart Emerald Coast celebrates Primary Stroke certification and honors care teams

 Ascension Sacred Heart Emerald Coast hosted a community ribbon-cutting ceremony Thursday, May 28 to celebrate earning its official Primary Stroke Center Certification. Awarded by The Joint Commission, the American Heart Association, and the American Stroke Association, this advanced designation ensures Walton County families have specialized, around-the-clock stroke care(NOT RECOVERY!) close to home.

The event, coordinated alongside the Walton Area Chamber of Commerce, brought together local leaders, community members and medical personnel. The milestone is uniquely critical to the region, as data shows that nearly 5% of adults in Walton County have experienced a stroke. A rate that is higher than the Florida state average. Between 2021 and 2023 alone, nearly 650 local residents were hospitalized due to strokes.

When a patient experiences a stroke, a lack of blood flow deprives brain cells of vital oxygen. According to the Centers for Disease Control and Prevention, a stroke occurs every 40 seconds in the United States. For every single minute that passes without intervention, an estimated 1.9 million brain cells are lost.

"When someone has a stroke, time is of the essence to ensure the best possible outcomes," said Trey Abshier, president and CEO of Sacred Heart Emerald Coast. "Our team has taken important steps to provide access to life-saving care(NOT RECOVERY!) to everyone in our community and surrounding region."

To meet these critical needs, the hospital maintains a dedicated, specialized infrastructure. This includes acute stroke teams, precise clinical protocols and advanced patient support systems designed to limit complications and maximize long-term recovery. 

A core focus of today's celebration was honoring the healthcare associates and local first responders who form the vital "chain of survival" for stroke patients.

During the ceremony, hospital leaders formally recognized a dedicated group of clinical personnel for their precision and speed in executing stroke alert protocols:

• Tracy Perk and Krisztina Matheny — Emergency Department Nursing Leaders
• Dr. Leif Skjerli — Emergency Department Physician
• Melinda Schlosser — Unit Coordinator
• Clinita Jones — CT Technologist
• Sonia Petrucci — Pharmacist 
• Will Farnham — Speech Pathologist
• Shannon Knight — Physical Therapist
• Evan Huesers - Emergency Department nurse

The event also highlighted the exceptional collaborative work of local emergency medical services (EMS) teams, whose rapid evaluation and field transfers ensure patients are delivered safely and swiftly to the hospital's specialized intervention teams.

The hospital extended its deepest gratitude to local first responders who recently demonstrated remarkable coordination during a critical stroke emergency:

• South Walton Fire District:
• Firefighter/Paramedic Shawn Ramsey
• Firefighter/EMT Marcus Cabanas
• Destin Fire Control District:
• Captain Firefighter/EMT Michael Anderson
• Engineer Firefighter/Paramedic Steven Eagerton
• Firefighter/EMT Fisher Morrison

Following a reflection and prayer delivered by the Rev. Dr. Joseph Shimko, attendees joined hospital leadership for the formal ribbon cutting, followed by an open reception to thank the community for its ongoing support of local healthcare.

For more information regarding local emergency and specialized services, visit GetSacredHeartCare.com or the hospital's regional resource site at ascension.org/EmeraldCoastFL.

Inside the Quest to Make Old Cells Young Again

 Ask your competent? doctor about the epigenetic restoration program. NO knowledge is grounds for IMMEDIATE DISMISSAL! I take no prisoners in trying to get stroke solved! A hell of a lot of dead wood needs to be removed!

Inside the Quest to Make Old Cells Young Again

Eric Spitznagel

June 12, 2026

 

For most of medical history, aging has been treated as a kind of slow damage accumulation, the body accruing wear the way a car does. A small army of researchers is now making a different argument, and the evidence behind it is starting to accumulate faster than anyone expected.

“The aging cell is a cell that’s lost metabolic fidelity,” said Eric Verdin, MD, president and CEO of the Buck Institute for Research on Aging, “and that loss is measurable, mechanistically grounded, and in principle correctable.”

That last phrase is doing a lot of heavy lifting. If cellular aging is correctable in principle, it may eventually be correctable in practice, which is why the field is attracting both serious science and serious money. Life Biosciences recently closed an $80 million funding round to advance its epigenetic restoration program into human trials — and a human received the first treatment this week. Meanwhile, Texas A&M researchers have created a nasal spray that calmed neuroinflammaging and restored more youthful mitochondria function in the brain.

Altered temporal variability-based functional reorganization of brain networks predicts motor outcome after stroke

 Predicting recovery rather than delivering recovery IS COMPLETE INCOMPETENCE!

I take no prisoners in trying to get stroke solved and that means a lot of dead wood needs to be removed. 

Altered temporal variability-based functional reorganization of brain networks predicts motor outcome after stroke

• Guojun Xu,
• Ling Li,
• Qinyang Li,
• Hewei Wang,
• Mingxia Fan,
• Limin Sun,
• Zhiyong Zhao &
• Hongxing Wang 

We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Abstract

Background

Dynamic functional connectivity (FC) studies have shown that motor recovery after stroke was associated with functional reorganization of brain networks. However, most previous studies have focused on interregional variability rather than the temporal variability (TV) of specific regions or networks. TV quantifies the dynamic reconfiguration of a region’s or network’s functional connectivity profile over time and reflects neural flexibility.

Purpose

This study investigated functional reorganization in chronic subcortical stroke using TV of brain networks derived from resting-state fMRI.

Methods

Thirty-three patients with left subcortical stroke (LSS), thirty with right subcortical stroke (RSS), and fifty-six age- and sex-matched healthy controls (HCs) were enrolled. Stroke patients underwent resting-state fMRI and Upper Extremity Fugl-Meyer Assessment (UE-FMA) at two time points. TV was computed to characterize dynamic functional connectivity at regional, intra-network, and inter-network levels. Group differences were assessed using one-way ANCOVA with post hoc tests. Linear regression was used to examine associations between TV and motor outcomes. The false discovery rate was used to multiple comparisons correction.

Results

Compared with HCs, both LSS and RSS showed significantly reduced TV in the right frontal-cingulate regions, the somatomotor hand network (SSH), and the connections between SSH and higher-order cognitive networks (all p < 0.05, |Cohen’s d| > 0.49). Increased TV was observed in the left postcentral gyrus, inferior frontal gyrus, cerebellar network (CEN), and somatomotor mouth network (all p < 0.05, |Cohen’s d| > 0.48). Relative to LSS, RSS exhibited additional TV reductions in the right middle occipital gyrus, orbital middle frontal gyrus, default mode network (DMN), and interactions among higher-order cognitive networks (all p < 0.05, |Cohen’s d| > 0.65). Notably, TV in the right opercular inferior frontal gyrus (IFGoperc) (β = 102.69, adjusted p = 6.4 × 10^− 5) and CEN (β = 27.87, adjusted p = 0.011) at the first observation positively correlated with UE-FMA scores at follow-up, with effects modulated by lesion laterality.

Conclusion

TV captures multiscale functional reorganization in chronic subcortical stroke involving motor, cognitive, and sensory networks. TV of the right IFGoperc showed potential as a neuroimaging biomarker for predicting post-stroke motor recovery.

Effortless Exercise Automatic Hand Trainer Gloves

 Have your competent? doctor validate that these are better than all these other ones out there. Can't do that? PURE INCOMPETENCE! I take no prisoners in getting stroke solved to 100% recovery. Aren't even trying to get there, then REMOVE THAT DEAD WOOD!

Gyroscopic glove (1)

HERO Grip Glove (1)

music glove (1)

RAPAEL Smart Glove (5)

SaeboGlove (1)

VTS Glove (2)

EsoGlove (1) 

glove (109 posts)

Effortless Exercise Automatic Hand Trainer Gloves 

So these gloves literally do hand rehabilitation exercises for you. You put them on, turn them on, and the built-in motors move each finger through a full range of motion automatically. No squeezing stress balls. No painful repetitive exercises you give up on after three days. The gloves do all the work while you sit there watching TV. This is a game changer for stroke recovery, arthritis, carpal tunnel, post surgery rehab, tendon injuries, or anyone dealing with hand stiffness and weakness. The biggest problem with hand therapy is that the people who need it most can't physically do the exercises on their own. These solve that completely. Multiple modes and intensity levels so you start gentle and increase as strength comes back over time. Rechargeable, portable, and quiet enough to wear anywhere. The kind of product that should be in every rehab center and every home where someone is recovering hand function. Genuinely surprised these aren't more mainstream yet. 💬 If you know someone recovering from a hand injury or stroke, send them this. Seriously. 🔗 Shop thousands of trending gadgets at Mavigadget.com 💰 Earn commissions — affiliate.mavigadget.com 🏪 Sell your products — partner.mavigadget.com hand trainer gloves, automatic hand exerciser, stroke recovery gloves, hand rehabilitation, arthritis gloves, finger therapy device, hand therapy gloves, grip recovery, carpal tunnel rehab, robotic rehab gloves, physical therapy hand, best stroke recovery tools #HandTrainer #StrokeRecovery #RehabGloves #Mavigadget #CoolGadgetsOpus 4.6 Extended

Mobile Stroke Units Enable Hyperacute Interventions for Intracerebral Hemorrhage

 Are they fast enough to get 100% recovery? If not; COMPLETE FUCKING FAILURE!

 The only goal in stroke is 100% recovery; if you're not there; GET THE HELL OUT OF STROKE! I take no prisoners in getting stroke solved, so if not following me; GET LOST!

Mobile Stroke Units Enable Hyperacute Interventions for Intracerebral Hemorrhage

Casandra MacLeod, DO, MS https://orcid.org/0009-0002-6918-3274 macleoc@ccf.org, Andrew Zhang, MD https://orcid.org/0000-0002-7801-8310, Nicolas Thompson, MS https://orcid.org/0000-0002-8973-5219, Elham Askari, MD, Merry Huang, MD, Nicholas Koroneos, DO, Maureen Buttrick, BSN, RN, … Show All … , and Jason Mathew, DO https://orcid.org/0000-0002-5862-687XAuthor Info & Affiliations

Stroke

New online

https://doi.org/10.1161/STROKEAHA.125.053752

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Abstract

BACKGROUND:

Mobile stroke units (MSUs) aim to expedite acute stroke management when compared with conventional emergency medical services (EMS). Despite the growing body of evidence surrounding MSUs and acute ischemic stroke, experience with intracerebral hemorrhage (ICH) in MSUs has been lacking. We aimed to evaluate the impact of MSU transportation, compared with EMS, on times to diagnosis and goal-directed treatment in patients with ICH.

METHODS:

Retrospective analysis of patients with acute ICH triaged by MSU or EMS from January 2018 to December 2022 was performed at 2 tertiary institutions, the Cleveland Clinic (OH) and Stony Brook University (NY). In the EMS cohort, only patients seen between 08:00 and 20:00, corresponding to the operating hours of MSU, were included. Primary outcomes included diagnosis by computed tomography, administration of antihypertensives, and time to goal systolic blood pressure (<160 mm Hg). Analyses included descriptive statistics and multivariable regression modeling of log-transformed time metrics, adjusting for important patient demographic and clinical characteristics.

RESULTS:

Among 540 patients screened with ICH, after removing those with exclusion criteria, 218 MSU patients were compared with 192 EMS patients. Cohorts had similar baseline demographics, majority male (53.7% MSU versus 49.5% EMS), mean age 67±14 and 68±16, respectively. MSUs reduced time to diagnosis by 28% (β=0.72 [95% CI, 0.62–0.82]; P<0.001). Antihypertensives were administered to 78% of MSU patients, whereas not routinely given to EMS-transported patients until emergency department arrival. This facilitated a time reduction of 54% in the administration time of antihypertensive medications in MSU compared with EMS transported patients (β, 0.46 [95% CI, 0.36–0.59]; P<0.001). With 87% of MSU patients achieving blood pressure goal within 1 hour from last known well, compared with 60% in EMS (P<0.001).

CONCLUSIONS:

MSUs provide faster diagnosis and medical treatment for patients with acute ICH than patients transported by conventional EMS.

Graphical Abstract

AI-powered stroke tool linked to improved patient outcomes in large clinical trial

 Have your competent? doctor get the EXACT PROTOCOL! Not being able to do that simple task IS PURE INCOMPETENCE! I take no prisoners in trying to get stroke solved, which means a lot of dead wood/brains need to find easier jobs.  The gap is not stroke 'care' you blithering idiots, it's RECOVERY! The only goal in stroke is 100% recovery. And I think a lot of funerals will need to occur before we get the right strategy and leadership to GET THERE!

Neils Bohr who famously said science progresses one funeral at a time.

It is the same in stroke? How many and who will have to die before we get 100% recovery protocols?

AI-powered stroke tool linked to improved patient outcomes in large clinical trial

• A new study suggests that a stroke clinical decision support system (CDSS), which uses artificial intelligence (AI) assisted imaging, could help to significantly reduce the risk of recurrent vascular events.
• Researchers suggest the AI tool is a safe intervention that provides the added benefits of lower cost and greater sustainability.
• In the large study, the AI-based system improved stroke care(NOT RECOVERY!) and outcomes, supporting its potential as a scalable tool for routine stroke care(NOT RECOVERY!), particularly in resource-limited settings.

Stroke is a significant global health concern and continues to be a leading cause of disability and death in the United States.

Evidence suggests that more than 795,000 peopleTrusted Source in the U.S. have a stroke each year, and nearly one in four of those are people who have had a previous stroke.

Clinicians play a critical role in preventing recurrent stroke. Typically, this occurs through implementing effective strategies, such as prevention plans, regular patient reviews, and addressing lifestyle modifications.

To assist with this, clinicians may consider clinical decision support systems (CDSS). These systems can help healthcare institutions analyze data from electronic health records and make recommendations to physicians by sending prompts and reminders in real-time

The potential scope of CDSS to help aid clinicians in complex decision-making processes for preventing stroke is increasing. However, many tools that utilize AI have not been rigorously evaluated, limiting their use.

Now, a large study published in The BMJTrusted Source suggests an AI-powered CDSS may improve the quality of care(NOT RECOVERY!) and long-term outcomes for people who experience an acute ischemic stroke.

The findings suggest that such systems could offer a scalable and cost-effective way to enhance stroke management, particularly in regions with limited healthcare resources.

Addressing a gap in stroke care(You are clueless if you think survivors want 'care'; NOT RECOVERY!)

The use of AI technologies has increasingly been explored in healthcare, particularly for diagnosing disease, predicting outcomes, and supporting clinical decision making.

However, many AI tools designed for stroke care(NOT RECOVERY!) have not yet undergone rigorous evaluation in real-world clinical settings, limiting their widespread adoption.

To address this, researchers in China conducted a large trial to assess whether an AI-assisted CDSS could improve care(NOT RECOVERY!) quality and patient outcomes in routine practice.

The system analyzes brain scans to classify stroke causes and combines this with evidence-based treatment recommendations tailored to individual patients.

The research team suggests that the AI-based tool was associated with a significant reduction in subsequent vascular events compared with standard care(NOT RECOVERY!).

Christopher Yi, MD, board certified vascular surgeon at MemorialCare Orange Coast Medical Center in Fountain Valley, CA, who was not involved in the study, suggests how AI could fit into stroke management.

“This study is the first of its kind to utilize AI for stroke care(NOT RECOVERY!) from being a diagnostic aid to being a tool that can improve care(NOT RECOVERY!) quality and reduce recurrent vascular events,” said Yi.

“In this study, the CDSS did more than read images: It integrated AI-assisted imaging, stroke-cause classification, reminders for needed evaluations, and guideline-based treatment recommendations,” he added.

“The biggest takeaway is that a well-integrated CDSS can help clinicians deliver more consistent evidence-based stroke care. It also helps guide interventionalists to better outcomes by improving stroke care quality and decreasing long term vascular events.”
– Christopher Yi, MD

Large-scale trial across 77 hospitals

The large study involved more than 21,000 participants with acute ischemic stroke admitted to 77 hospitals across China within 7 days of symptom onset. The individuals had an average age of 67, and just over one-third were female.

Between January 2021 and June 2023, 11,054 people received treatment at 38 hospitals supported by the AI-based CDSS. The other 10,549 participants at 39 hospitals received usual medical care.

Physicians in the intervention group were trained to use the system. The CDSS incorporated a range of patient-specific factors, including age, medical history, lifestyle, and hospital characteristics, when generating recommendations.