Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there. Did your doctor somehow miss the recovery protocol that Pedro Bach-y-Rita used to recover fully back in 1958 with only a partial brain?

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Showing posts with label statistics. Show all posts
Showing posts with label statistics. Show all posts

Monday, October 26, 2026

18+ million views of this blog


I must still be interesting to some people. I have never received any direct communications from any stroke medical 'professionals'. Are they scared to talk to me?

First million took from Aug. 2010  to Sept. 2014

Second million from Sept. 2014 to May 2016

Third million from May 2016 to March 2017

Fourth million from March 2017 to November 2018

Fifth million from November 2018 to September 2021

Sixth million from September 2021 to June 2024

Seventh million was from June 2024 to January 2025. 

Eighth million was from January 2025 to June 2025

Ninth million was from June 2025 to September 2025;

Tenth million was from September 2025 to January 2026

Eleventh million was from January 2026 to April 2026

Twelfth million from April 2026 to June 2026

Thirteen million from June 2026 to July 2026

Fourteen million from July 2026 to September 2026

14-18 million from September 2026 to October 2026

Views are not accurate anymore:  Yes, web crawlers, AI scraping bots, and spam spiders are heavily inflating view statistics in Blogger. Unlike advanced analytic engines, Blogger's built-in "Stats" dashboard operates closer to raw server logs, meaning it records almost every script execution, ping, and automated request as a valid page view.

The first post was:



What my doctor should have told me about stroke recovery

Still has the same relevance today. And I'm still as arrogant and opinionated as ever. Arrogance is only true if you don't know what you're talking about! I do know what I'm talking about! 

Your doctor really knows nothing SPECIFIC AND EXACT to get you recovered. Ask him/her; you'll get dissembling rather than specifics! Or you'll get the craptastic saying: 'All strokes are different, all stroke recoveries are different'. In my opinion, that is the comment of a totally incompetent doctor!

Wednesday, September 30, 2026

14 million views of this blog

 

I must still be interesting to some people. I have never received any direct communications from any stroke medical 'professionals'. Are they scared to talk to me?

First million took from Aug. 2010  to Sept. 2014

Second million from Sept. 2014 to May 2016

Third million from May 2016 to March 2017

Fourth million from March 2017 to November 2018

Fifth million from November 2018 to September 2021

Sixth million from September 2021 to June 2024

Seventh million was from June 2024 to January 2025. 

Eighth million was from January 2025 to June 2025

Ninth million was from June 2025 to September 2025;

Tenth million was from September 2025 to January 2026

Eleventh million was from January 2026 to April 2026

Twelfth million from April 2026 to June 2026

Thirteen million from June 2026 to July 2026

Fourteen million from July 2026 to September 2026

The first post was:



What my doctor should have told me about stroke recovery

Still has the same relevance today. And I'm still as arrogant and opinionated as ever. Arrogance is only true if you don't know what you're talking about! I do know what I'm talking about! 

Your doctor really knows nothing SPECIFIC AND EXACT to get you recovered. Ask him/her; you'll get dissembling rather than specifics! Or you'll get the craptastic saying: 'All strokes are different, all stroke recoveries are different'. In my opinion, that is the comment of a totally incompetent doctor!

Thursday, July 30, 2026

13 million views of this blog

 

I must still be interesting to some people. I have never received any direct communications from any stroke medical 'professionals'. Are they scared to talk to me?

First million took from Aug. 2010  to Sept. 2014

Second million from Sept. 2014 to May 2016

Third million from May 2016 to March 2017

Fourth million from March 2017 to November 2018

Fifth million from November 2018 to September 2021

Sixth million from September 2021 to June 2024

Seventh million was from June 2024 to January 2025. 

Eighth million was from January 2025 to June 2025

Ninth million was from June 2025 to September 2025;

Tenth million was from September 2025 to January 2026

Eleventh million was from January 2026 to April 2026

Twelfth million from April 2026 to June 2026

Thirteen million from June 2026 to July 2026

The first post was:



What my doctor should have told me about stroke recovery

Still has the same relevance today. And I'm still as arrogant and opinionated as ever. Arrogance is only true if you don't know what you're talking about! I do know what I'm talking about! 

Your doctor really knows nothing SPECIFIC AND EXACT to get you recovered. Ask him/her; you'll get dissembling rather than specifics! Or you'll get the craptastic saying: 'All strokes are different, all stroke recoveries are different'. In my opinion, that is the comment of a totally incompetent doctor!

Thursday, June 25, 2026

12 million views of this blog

 

 I must still be interesting to some people. I have never received any direct communications from any stroke medical 'professionals'. Are they scared to talk to me?

First million took from Aug. 2010  to Sept. 2014

Second million from Sept. 2014 to May 2016

Third million from May 2016 to March 2017

Fourth million from March 2017 to November 2018

Fifth million from November 2018 to September 2021

Sixth million from September 2021 to June 2024

Seventh million was from June 2024 to January 2025. 

Eighth million was from January 2025 to June 2025

Ninth million was from June 2025 to September 2025;

Tenth million was from September 2025 to January 2026

Eleventh million was from January 2026 to April 2026

Twelfth million from April 2026 to June 2026

The first post was:



What my doctor should have told me about stroke recovery

Still has the same relevance today. And I'm still as arrogant and opinionated as ever. Arrogance is only true if you don't know what you're talking about! I do know what I'm talking about! 

Your doctor really knows nothing SPECIFIC AND EXACT to get you recovered. Ask him/her; you'll get dissembling rather than specifics! Or you'll get the craptastic saying: 'All strokes are different, all stroke recoveries are different'. In my opinion, that is the comment of a totally incompetent doctor!

Monday, April 13, 2026

11 million views of this blog

 

 I must still be interesting to some people. I have never received any direct communications from any stroke medical 'professionals'. Are they scared to talk to me?

First million took from Aug. 2010  to Sept. 2014

Second million from Sept. 2014 to May 2016

Third million from May 2016 to March 2017

Fourth million from March 2017 to November 2018

Fifth million from November 2018 to September 2021

Sixth million from September 2021 to June 2024

Seventh million was from June 2024 to January 2025. 

Eighth million was from January 2025 to June 2025

Ninth million was from June 2025 to September 2025;

Tenth million was from September 2025 to January 2026

Eleventh million was from January 2026 to April 2026

The first post was:



What my doctor should have told me about stroke recovery

Still has the same relevance today. And I'm still as arrogant and opinionated as ever. Arrogance is only true if you don't know what you're talking about! I do know what I'm talking about! 

Your doctor really knows nothing SPECIFIC AND EXACT to get you recovered. Ask him/her; you'll get dissembling rather than specifics! Or you'll get the craptastic saying: 'All strokes are different, all stroke recoveries are different'. In my opinion, that is the comment of a totally incompetent doctor!

Friday, January 30, 2026

10 million views of this blog

 

 I must still be interesting to some people. I have never received any direct communications from any stroke medical 'professionals'. Are they scared to talk to me?

First million took from Aug. 2010  to Sept. 2014
Second million from Sept. 2014 to May 2016
Third million from May 2016 to March 2017
Fourth million from March 2017 to November 2018
Fifth million from November 2018 to September 2021

Sixth million from September 2021 to June 2024

Seventh million was from June 2024 to January 2025. 

Eighth million was from January 2025 to June 2025

Ninth million was from June 2025 to September 2025;

Tenth million was from September 2025 to January 2026

The first post was:



What my doctor should have told me about stroke recovery

Still has the same relevance today. And I'm still as arrogant and opinionated as ever. Arrogance is only true if you don't know what you're talking about! I do know what I'm talking about! 

Your doctor really knows nothing SPECIFIC AND EXACT to get you recovered. Ask him/her; you'll get dissembling rather than specifics! Or you'll get the craptastic saying: 'All strokes are different, all stroke recoveries are different'. In my opinion, that is the comment of a totally incompetent doctor!

Tuesday, September 30, 2025

9 million views of this blog

 

 I must still be interesting to some people. I have never received any direct communications from any stroke medical 'professionals'. Are they scared to talk to me?

First million took from Aug. 2010  to Sept. 2014
Second million from Sept. 2014 to May 2016
Third million from May 2016 to March 2017
Fourth million from March 2017 to November 2018
Fifth million from November 2018 to September 2021

Sixth million from September 2021 to June 2024

Seventh million was from June 2024 to January 2025. 

Eighth million was from January 2025 to June 2025

Ninth million was from June 2025 to September 2025;'


The first post was:



What my doctor should have told me about stroke recovery

Still has the same relevance today. And I'm still as arrogant and opinionated as ever. Arrogance is only true if you don't know what you're talking about! I do know what I'm talking about! 

Your doctor really knows nothing SPECIFIC AND EXACT to get you recovered. Ask him/her; you'll get dissembling rather than specifics! Or you'll get the craptastic saying: 'All strokes are different, all stroke recoveries are different'. In my opinion, that is the comment of a totally incompetent doctor!

Saturday, May 31, 2025

8 million views of this blog

 

 I must still be interesting to some people. I have never received any direct communications from any stroke medical 'professionals'. Are they scared to talk to me?
First million took from Aug. 2010  to Sept. 2014
Second million from Sept. 2014 to May 2016
Third million from May 2016 to March 2017
Fourth million from March 2017 to November 2018
Fifth million from November 2018 to September 2021

Sixth million from September 2021 to June 2024

Seventh million was from June 2024 to January 2025. 

Eighth million was from January 2025 to June 2025

The first post was:



What my doctor should have told me about stroke recovery

Still has the same relevance today. And I'm still as arrogant and opinionated as ever. Arrogance is only true if you don't know what you're talking about! I do know what I'm talking about!

Friday, April 4, 2025

30,000 blog posts

 

When I first started writing this blog 15+ years ago as suggested by Peter Levine, my only goal was to beat him in number of views and find and report on useful rehab. Did that in about 1.5 years. The goal changed to document all the ways survivors could be treated better and get a lot more recovery. This would be quite easy to do if we had the strategy, leadership and foundation money to followup the thousands upon thousands of promising research trials and translate them into valid stroke rehab intervention protocols.
I can't tell if this blog is doing one damn bit of good, not a single doctor that I know of has even commented on this. And the presidents of our fucking failures of stroke associations  haven't contacted me.  I'm sure some employees of those associations know about this but are too scared to tell their president.
I know I have at least 10,000 more posts coming since stroke research is never correlated to any stroke strategy.  I don't see stroke being solved to 100% recovery in the 31 years I have left(age 100).

10,000 posts took from Sept. 2010 to May 2016

The next 10,000 took from May 2016 to Sept. 2020

The next 10,000 took from Sept. 2020 to April 2025  

Thursday, January 23, 2025

7 million views of this blog

 

 I must still be interesting to some people. I have never received any direct communications from any stroke medical 'professionals'. Are they scared to talk to me?
First million took from Aug. 2010  to Sept. 2014
Second million from Sept. 2014 to May 2016
Third million from May 2016 to March 2017
Fourth million from March 2017 to November 2018
Fifth million from November 2018 to September 2021

Sixth million from September 2021 to June 2024

Seventh million was from June2024 to January 2025. 

The first post was:



What my doctor should have told me about stroke recovery

Still has the same relevance today. And I'm still as arrogant and opinionated as ever. Arrogance is only true if you don't know what you're talking about! I do know what I'm talking about!

Sunday, October 27, 2024

Brain Blood Flow Issues Linked to Mild Cognitive Impairment

 And I bet your competent? doctor DID NOTHING immediately post stroke to improve your cerebral blood flow and oxygen delivery to try and save those neurons about to die from the neuronal cascade of death in the first week.  

Maybe these, why isn't your incompetent doctor already delivering these to you?
  • cerebral blood flow (36 posts to July 2016)
  • oxygen delivery (31 posts to January 2020)

  • I'd suggest charging your doctor $1000 a neuron that died in the first week. 

    Here are the calculations I put together:

    My calculation is that my doctors let 

    5.4 billion neurons die. 

    21,600 miles dead myelinated fibers 

    2.8 trillion dead synapses 
    All in the first week!

    Day 1: first 90 minutes:
    171 million dead neurons 
    1.260 trillion dead synapses
    675 miles of dead myelinated fibers
    Brain aged 5.4 years
    ----------------------------------------------------------------------------
    Days 2-3:
    So 1440 minutes a day * 2days * 950000 = 2,736,000,000  or 2.7 billion  dead neurons
      1440 minutes a day *2days * 7,000,000,000syn = 20,160,000,000,000     20.2 trillion        dead synapses
    1440 * 2days * 3.75mi = 10800 mi  dead myelinated fibers
    Brain aged - 2 years, a guess
    ------------------------------------------------------------------------------
    Days 4-7:
    So 1440 minutes a day * 4days * 475000 = 2,736,000,000  or 2.7 billion dead neurons
      1440 minutes a day *4days * 3,500,000,000syn = 20,160,000,000,000 20.2 trillion    dead synapses
    1440 * 4days * 1.875mi = 10800 mi  dead myelinated fibers
    Brain aged - 2 years, a guess 
    -------------------------------------------------------------------------
    This is one hell of a lot of damage to recover from. Especially since we don't know how to move functions from dead locations to new ones.  Or know how to usefully get neurogenesis to work.
    -----------------------------------------------------------------------------
    Totals:
    5.571 billion dead neurons
    4.041260 trillion dead synapses
     22,275 miles dead myelinated fibers
    Brain aged -  9.4 years
    ---------------------------------------------------------------------------------
    The brain contains 80 billion neurons, I only lost 6.96375% of my brain.  
    My charge would be $5.57100000E+15, whatever that is in real terms, beyond my calculators capacity. 

    Damn hard to recover from all that with no stroke protocols.    

    Brain Blood Flow Issues Linked to Mild Cognitive Impairment

    Summary: Older adults with mild cognitive impairment (MCI) face higher cerebrovascular impedance, or resistance in brain blood flow, according to a new study. Researchers found this increased resistance leads to hypoperfusion, or reduced blood flow in the brain, which may contribute to cognitive difficulties in aging adults.

    By using ultrasound and blood pressure tools, scientists analyzed brain blood flow in 58 older adults with MCI and 25 without, discovering a significant difference in cerebrovascular health between the two groups.

    This finding suggests vascular function plays a vital role in maintaining cognitive health. The study opens new avenues for exploring interventions to improve blood flow and support cognitive function in older adults at risk of Alzheimer’s.

    Key Facts

    • Increased cerebrovascular impedance in MCI patients lowers brain blood flow.
    • Hypoperfusion from blood flow resistance may worsen cognitive symptoms.
    • The study suggests vascular health is crucial for cognitive function in aging.

    Source: American Physiological Society

    Older adults with mild cognitive impairment showed greater resistance to brain blood flow compared to those without cognitive impediments.

    The first-of-its-kind study is published in the Journal of Applied Physiology and has been chosen as an APSselect article for October.  

    This shows brain scans.
    The research team found the volunteers with mild cognitive impairment had higher cerebrovascular impedance and, in turn, decreased blood flow (hypoperfusion) through the brain. Credit: Neuroscience News

    Brain blood flow resistance (also called cerebrovascular impedance) is linked to cognitive problems, which can manifest in several ways, including:

    • Difficulty remembering recent events.
    • Difficulty finding the right word or remembering a name.
    • Difficulty focusing on a task.
    • Disorientation in time and space. 

    The purpose of the study was to determine if mild cognitive impairment affects the brain’s blood vessels’ ability to transport blood.

    Using blood pressure instruments and ultrasonogram imaging to measure impedance in the brain’s blood vessels, the research team studied 58 older adults with mild cognitive impairment who have a higher risk for developing Alzheimer’s disease.

    The researchers compared these participants to 25 age-matched volunteers with normal cognition.

    The research team found the volunteers with mild cognitive impairment had higher cerebrovascular impedance and, in turn, decreased blood flow (hypoperfusion) through the brain.

    Hypoperfusion can lead to cognitive problems in older adults.

    “These findings shed light on the pathophysiological mechanisms of brain hypoperfusion in older adults who have a high risk of [Alzheimer’s disease],” the researchers wrote.

    “This study highlights the importance of brain vascular function in brain health in older adults,” said Rong Zhang, PhD, a professor of neurology and senior author of the study.

    About this cognition and aging research news

    Author: Erica Roth
    Source: American Physiological Society
    Contact: Erica Roth – American Physiological Society
    Image: The image is credited to Neuroscience News

    Original Research: Open access.
    “Patients with amnestic mild cognitive impairment have higher cerebrovascular impedance than cognitively normal older adults” by Rong Zhang et al. Journal of Applied Physiology

    Wednesday, June 19, 2024

    6 million views of this blog

     

     I must still be interesting to some people. I have never received any direct communications from any stroke medical 'professionals'. Are they scared to talk to me?
    First million took from Aug. 2010  to Sept. 2014
    Second million from Sept. 2014 to May 2016
    Third million from May 2016 to March 2017
    Fourth million from March 2017 to November 2018
    Fifth million from November 2018 to September 2021

    Sixth million from September 2021 to June 2024 

    The first post was:



    What my doctor should have told me about stroke recovery

    Still has the same relevance today. And I'm still as arrogant and opinionated as ever.

    Sunday, October 23, 2022

    Global stroke statistics 2022

     

     What an absolute useless pile of shit. NOTHING ON 100% RECOVERY! Just maybe stroke survivors might want to know that.

    “What's measured, improves.” So said management legend and author Peter F. Drucker 

    Global stroke statistics 2022

    Abstract

    Background:

    Contemporary data on stroke epidemiology and the availability of national stroke clinical registries are important for providing evidence to improve practice and support policy decisions.

    Aims:

    To update the most current incidence, case-fatality, and mortality rates on stroke and identify national stroke clinical registries worldwide.

    Methods:

    We searched multiple databases (based on our existing search strategy) to identify new original papers, published between 1 November 2018 and 15 December 2021, that met ideal criteria for data on stroke incidence and case-fatality, and added these to the studies reported in our last review. To identify national stroke clinical registries, we updated our last search, using PubMed, from 6 February 2015 until 6 January 2022. We also screened reference lists of review papers, citation history of papers, and the gray literature. Mortality codes for International Classification of Diseases (ICD)-9 and ICD-10 were extracted from the World Health Organization (WHO) for each country providing these data. Population denominators were obtained from the United Nations (UN) or WHO (when data were unavailable in the UN database). Crude and adjusted stroke mortality rates were calculated using country-specific population denominators, and the most recent years of mortality data available for each country.

    Results:

    Since our last report in 2020, there were two countries (Chile and France) with new incidence studies meeting criteria for ideal population-based studies. New data on case-fatality were found for Chile and Kenya. The most current mortality data were available for the year 2014 (1 country), 2015 (2 countries), 2016 (11 countries), 2017 (10 countries), 2018 (19 countries), 2019 (36 countries), and 2020 (29 countries). Four countries (Libya, Solomon Islands, United Arab Emirates, and Lebanon) reported mortality data for the first time. Since our last report on registries in 2017, we identified seven more national stroke clinical registries, predominantly in high-income countries. These newly identified registries yielded limited information.

    Conclusions:

    Up-to-date data on stroke incidence, case-fatality, and mortality continue to provide evidence of disparities and the scale of burden in low- and middle-income countries. Although more national stroke clinical registries were identified, information from these newly identified registries was limited. Highlighting data scarcity or even where a country is ranked might help facilitate more research or greater policy attention in this field.

    Introduction

    The worldwide burden of stroke remains massive, and there is a continued need to understand trends of the disease and its impact on each country, to guide policy decisions and healthcare planning. We have previously reported stroke statistics by country.1–3 We have also previously recognized the value of national stroke clinical registries, not just for routine monitoring of patient characteristics, access to clinical care, and health outcomes, but also their potential to be a reliable supplement or substitute for epidemiological studies in countries where a large proportion of the population is hospitalized.3,4 This fourth issue is part of an ongoing series to update information on (1) stroke incidence, case-fatality and mortality, and availability of national stroke clinical registries around the world; and (2) highlight where data are lacking or outdated.

    Sunday, August 28, 2022

    Global Stroke Statistics 2022

     What an absolute useless pile of shit. NOTHING ON 100% RECOVERY! Just maybe stroke survivors might want to know that.

    “What's measured, improves.” So said management legend and author Peter F. Drucker 

    Global Stroke Statistics 2022

    First Published August 17, 2022 Research Article 

    Background: 

    Contemporary data on stroke epidemiology and the availability of national stroke clinical registries are important for providing evidence to improve practice and support policy decisions.

    Aims: 

    To update the most current incidence, case-fatality and mortality rates on stroke, and identify national stroke clinical registries worldwide.

    Methods: 

    We searched multiple databases (based on our existing search strategy) to identify new original papers, published between 1 November 2018 and 15 December 2021, that met ideal criteria for data on stroke incidence and case-fatality, and added these to the studies reported in our last review. To identify national stroke clinical registries, we updated our last search, using PubMed, from 6 February 2015 until 6 January 2022. We also screened reference lists of review papers, citation history of papers and the grey literature. Mortality codes for ICD-9 and ICD-10 were extracted from the World Health Organization (WHO) for each country providing these data. Population denominators were obtained from the United Nations (UN) or WHO (when data were unavailable in the UN database). Crude and adjusted stroke mortality rates were calculated using country-specific population denominators and the most recent years of mortality data available for each country.

    Results: 

    Since our last report in 2020, there were two countries (Chile and France) with new incidence studies meeting criteria for ideal population-based studies. New data on case-fatality were found for Chile and Kenya. The most current mortality data were available for the year 2014 (1 country), 2015 (2 countries), 2016 (11 countries), 2017 (10 countries), 2018 (19 countries), 2019 (36 countries), and 2020 (29 countries). Four countries (Libya, Solomon Islands, United Arab Emirates, and Lebanon) reported mortality data for the first time. Since our last report on registries in 2017, we identified seven more national stroke clinical registries, predominantly in high income countries. These newly identified registries yielded limited information.

    Conclusions: 

    Up-to-date data on stroke incidence, case-fatality and mortality continues to provide evidence of disparities and the scale of burden in low- and middle-income countries. Although more national stroke clinical registries were identified, information from these newly identified registries were limited. Highlighting data scarcity or even where a country is ranked might help facilitate more research or greater policy attention in this field.

    Thursday, January 20, 2022

    World Stroke Organization (WSO): Global Stroke Fact Sheet 2022

     I'm sure I can guarantee that nothing in here tells us how many survivors 100% recovered, which means the WSO doesn't care about stroke recovery. Because stroke statistics do nothing to help survivors recover. The WSO is completely useless for survivors.

    World Stroke Organization (WSO): Global Stroke Fact Sheet 2022

    First Published January 5, 2022 Review Article Find in PubMed 

    Stroke remains the second-leading cause of death and the third-leading cause of death and disability combined (as expressed by disability-adjusted life-years lost – DALYs) in the world. The estimated global cost of stroke is over US$721 billion (0.66% of the global GDP). From 1990 to 2019, the burden (in terms of the absolute number of cases) increased substantially (70.0% increase in incident strokes, 43.0% deaths from stroke, 102.0% prevalent strokes, and 143.0% DALYs), with the bulk of the global stroke burden (86.0% of deaths and 89.0% of DALYs) residing in lower-income and lower-middle-income countries (LMIC). This World Stroke Organisation (WSO) Global Stroke Fact Sheet 2022 provides the most updated information that can be used to inform communication with all internal and external stakeholders; all statistics have been reviewed and approved for use by the WSO Executive Committee as well as leaders from the Global Burden of Disease research group.

     

    Tuesday, September 21, 2021

    5 million views of this blog

     I must still be interesting to some people. I have never received any direct communications from any stroke medical professionals. Are they scared to talk to me?
    First million took from Aug. 2010  to Sept. 2014
    Second million from Sept. 2014 to May 2016
    Third million from May 2016 to March 2017
    Fourth million from March 2017 to November 2018
    Fifth million from November 2018 to September 2021

    The first post was:



    What my doctor should have told me about stroke recovery

    Still has the same relevance today. And I'm still as arrogant and opinionated as ever.

    Monday, June 21, 2021

    Clinical characteristics of fast and slow progressors of infarct growth in anterior circulation large vessel occlusion stroke

     Pretty much useless since all the other measurements of damages are in understandable figures.

    In each  untreated minute,

    1.9 million neurons die

    14 billion synapses die

    12 km (7.5 miles) of myelinated fibers die

    brain ages 3.6 years each hour without treatment

    Clinical characteristics of fast and slow progressors of infarct growth in anterior circulation large vessel occlusion stroke

    First Published June 17, 2021 Research Article 

    Fast and slow progressor phenotypes of infarct growth due to anterior circulation large vessel occlusion (ACLVO) remain poorly understood. We aimed to define clinical predictors of fast and slow progressors in a retrospective study of patients with ACLVO who underwent baseline advanced imaging within 24 hours of stroke onset. Fast progressors (ischemic core > 70 ml, < 6 hours after onset) and slow progressors (ischemic core ≤ 30 ml, 6 to 24 hours after onset) were identified amongst 185 patients. Clinical and laboratory variables were tested for association with fast or slow progressor status. In the early epoch, no significant differences were found between fast progressors and controls. In the delayed epoch, slow progressors had a median NIHSS of 14 versus 20 (p < 0.01) and MCA occlusion in 80% versus 63% (p < 0.05) relative to controls. In multivariate analyses, NIHSS (OR 0.83, 95% CI 0.73-0.95), hyperlipidemia (OR 4.24, 95% CI 1.01 – 19.3) and hemoglobin concentration (OR 0.75, 95% CI 0.57 – 0.99) were independently associated with slow progressor status. This study indicates that lower initial stroke symptom severity, a history of hyperlipidemia and mild anemia are associated with individual tolerance to ACLVO stroke.

     

    Friday, June 11, 2021

    Some statisical mumbo jumbo

     Thought I 'd look at the frequency of my index entries. Top 11. I am rather eloquent in my verbal swearing. Your doctor has a lot to answer for.

    Wednesday, December 16, 2020

    Statistical Considerations for Drawing Conclusions About Recovery

     So our researchers know nothing about what their research says.

    Statistical Considerations for Drawing Conclusions About Recovery

     
    First Published December 14, 2020 Research Article 

    Numerous studies have found associations when change scores are regressed onto initial impairments in people with stroke (slopes ≈ 0.7). However, there are important statistical considerations that limit the conclusions we can draw about recovery from these studies.

    To provide an accessible checklist of conceptual and analytical issues on longitudinal measures of stroke recovery. Proportional recovery is an illustrative example, but these considerations apply broadly to studies of change over time.

    Using a pooled data set of n = 373 Fugl-Meyer Assessment upper extremity scores, we ran simulations to illustrate 3 considerations: (1) how change scores can be problematic in this context; (2) how “nil” and nonzero null-hypothesis significance tests can be used; and (3) how scale boundaries can create the illusion of proportionality, whereas other analytical procedures (eg, post hoc classifications) can augment this problem.

    Our simulations highlight several limitations of common methods for analyzing recovery. We find that uniform recovery leads to similar group-level statistics (regression slopes) and individual-level classifications (into fitters and nonfitters) that have been claimed as evidence for the proportional recovery rule. New analyses, however, also speak to the complexities in variance about the regression slope.

    Our results highlight that one cannot identify whether proportional recovery is true or not based on commonly used methods. We illustrate how these techniques, measurement tools, and post hoc classifications (eg, nonfitters) can create spurious results. Going forward, the field needs to carefully consider the influence of these factors on how we measure, analyze, and conceptualize recovery.

    Access Options

    Wednesday, September 2, 2020

    20,000 blog posts

     When I first started writing this blog 10 years ago as suggested by Peter Levine, my only goal was to beat him in number of views and find and report on useful rehab. Did that in about 1.5 years. The goal changed to document all the ways survivors could be treated better and get a lot more recovery. This would be quite easy to do if we had the strategy and foundation money to followup the thousands upon thousands of promising research trials and translate them into valid stroke rehab intervention protocols.
    I can't tell if this blog is doing one damn bit of good, not a single doctor that I know of has even commented  on this. And the presidents of our fucking failures of stroke associations  haven't contacted me.  I'm sure some employees of those associations know about this but are too scared to tell their president.
    I know I have at least 10,000 more posts coming since stroke research is never correlated to any stroke strategy. 

    10,000 posts took from Sept. 2010 to May 2016

    The next 10,000 took from May 2016 to Sept. 2020