Deans' stroke musings: The relationship between the functional status of upper extremity motor neurons and motor function and prognosis in stroke patients

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, September 23, 2024

The relationship between the functional status of upper extremity motor neurons and motor function and prognosis in stroke patients

NOTHING HERE HELPS STROKE RECOVERY! What the fuck was the research for? I'd have all of you fired! What we have for stroke leadership is so fucking bad that I really do hope schadenfreude hits them all so they finally understand stroke survivor pain and frustration.

The relationship between the functional status of upper extremity motor neurons and motor function and prognosis in stroke patients

Xiaoyi Li¹

Zhen Shao²

Zhi Li¹

Xiupan Wei¹

Lijuan Zong¹

Pei Wang¹

Ting Zhou¹

Hongxing Wang¹^*

¹Department of Rehabilitation Medicine, Zhongda Hospital Southeast University, School of Medicine, Southeast University, Nanjing, China
²Department of Rehabilitation Medicine, Affiliated Hospital of Xuzhou Medical University, Xuzhou, China

Introduction: This study investigates the correlation between neuroelectrop-hysiological assessments such as motor unit number estimation (MUNE) and F-waves with upper extremity motor function and one-year prognosis in stroke patients.

Methods: Neuroelectrophysiological assessments of the abductor pollicis brevis muscle, including MUNE and F-waves, were conducted. Upper extremity motor function was evaluated using the Fugl-Meyer Assessment of Upper Extremity (FMA-UE) and the Modified Ashworth Scale (MAS). Pearson correlation and multiple linear regression analyses were performed to explore the relationship between upper extremity motor function and variables such as MUNE and F-waves. ROC curve analysis assessed the predictive ability of MUNE and F-waves for upper extremity motor function, and binary logistic regression analysis examined factors related to motor function improvement 1 year post-discharge.

Results: A total of 130 patients were ultimately included. Significant differences in MUNE and occupancy rate of non-repeater F-waves (non-ORF) were found between hemiplegic and unaffected sides (p < 0.001), with a significant difference in F-wave mean latency (p < 0.05). Pearson correlation analysis showed a positive correlation between FMA-UE at admission and hemiplegic side’s MUNE and non-ORF (p < 0.001). Multiple linear regression indicated that hemiplegic side’s MUNE (β = 0.88, p < 0.001) and non-ORF (β = 0.275, p = 0.005) influenced FMA-UE. ROC analysis demonstrated higher predictive ability for hemiplegic side’s MUNE (AUC = 0.696, p < 0.001) than non-ORF (AUC = 0.622, p = 0.018). Binary logistic regression showed that hemiplegic side’s MUNE was associated with FMA-UE improvement 1 year post-discharge.

Conclusion: MUNE and F-waves are correlated with upper extremity motor function in patients, reflecting their motor function status. These indicators have good predictive value for motor function and are associated with the prognosis of upper extremity motor function to a certain extent.