And if our fucking failures of stroke associations were any good at all they would have similar articles published. But no, all is well in the rose colored world of the stroke associations. F.A.S.T. and tPA are working great, we just need more awareness so F.A.S.T. and tPA can either prevent or solve all strokes. The blinders are large in our stroke associations, I blame the boards of directors for not setting goals correctly.
http://neurosciencenews.com/alzheimers-epidemiology-2050-3360/
UCLA biostatistics team forecasts prevalence of the disease under different circumstances.
We’re living longer. The number of U.S. adults 65 and older — roughly
40 million as of the 2010 census — is expected to nearly double to 71
million by 2030 and to reach 98 million by 2060. In much of the rest of
the world, the story is the same. But if the aging trend illustrates the
success of public health strategies, it also raises the specter of a
major public health crisis — a sharp rise in the number of people living
with Alzheimer’s disease.
Ron Brookmeyer, a professor in the UCLA Fielding School of Public Health’s Department of Biostatistics,
has called attention to the looming Alzheimer’s epidemic through widely
cited studies in which he has employed sophisticated computer models to
project the number of cases, as well as the potential positive impact
of future therapies and other strategies to prevent or delay the onset
and progression of symptoms.
Brookmeyer’s work in this arena began nearly 20 years ago with a
paper he wrote in the American Journal of Public Health projecting that
the prevalence of Alzheimer’s disease
in the United States would nearly quadruple by the middle of this
century, by which time approximately 1 in 45 Americans will be
afflicted. His 2007 study also projected that 1 in 85 persons worldwide
will be living with the disease by 2050, with nearly half of them
requiring a level of care equivalent to that of a nursing home.
Brookmeyer’s development of statistical models to make forecasts on
epidemics began in the late 1980s with HIV/AIDS, but after becoming
involved in a study on aging, he turned his attention to the threat
posed by Alzheimer’s disease. “Obviously it’s not a transmissible
epidemic like the ones I had been looking at, but with the aging of the
population, it was clear that the numbers were going to explode,” he
explains.
As part of his modeling, Brookmeyer and his colleagues consider both
demographic trends and the severity of the progression of the disease.
“This is a long illness,” he says. “Once you’re diagnosed, you might
live with it for 10 or more years, and the intensity of the care
required will vary during that time. From a public health point of view,
it’s very important to look at where people will be in different stages
of the disease and the needs we will be facing as a society.”
Through a systematic review of Alzheimer’s studies, Brookmeyer’s team
has found that the rate of being diagnosed with the disease doubles
every five years in older populations. For example, the likelihood of a
diagnosis at age 77 is approximately 1 percent; by age 82 it is 2
percent, and at age 87 it is 4 percent. This rate of increase with aging
is consistent across the world. Combining those factors with trends in
other causes of aging-related mortality, such as cardiovascular disease
and cancer, the group forecasts the future prevalence of Alzheimer’s
disease.
Equally important, the modeling also allows Brookmeyer and colleagues
to factor in the future impact of advances in Alzheimer’s disease
prevention and treatment — what Brookmeyer calls “what if” scenarios.
“What if we could delay the onset of the disease for a few years?” he
says. “In an aging population, even modest advances could be home runs
in terms of their public health impact.” For example, Brookmeyer has
found that if an intervention could delay the average disease onset by
even a single year, it would reduce by 9 million the number of projected
worldwide cases by mid-century.
Brookmeyer
is currently working with researchers at UC Irvine on a study of “the
oldest old” — persons over the age of 90, the fastest- growing segment
of the U.S. population — to better understand the predictors of
successful aging and factors that might protect against dementia. The
study follows a cohort of individuals living in a retirement center who,
as far back as the 1980s, began filling out detailed questionnaires
designed to capture lifestyle characteristics. “Over the next 50 years
in the U.S., the over-90 population is going to grow six-fold, so this
is a very important group to understand when it comes to the issue of
dementia,” Brookmeyer says.
While Brookmeyer’s projections of the increase in Alzheimer’s paint a
bleak picture, given the current state of prevention and treatment, he
points out that recent developments in the field offer plenty of room
for optimism.
There have been new insights into how the disease develops, as well
as the identification of new biomarkers that can assist in diagnosing
Alzheimer’s and tracking the impact of potential therapies. “Among the
most promising interventions currently under investigation are those
that target the buildup of amyloid beta proteins in an effort to slow
the onset and progression of Alzheimer’s,” Brookmeyer says.
Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 29,116 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
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