Finally some researchers doing some correct research. What the hell makes these so special and correct and all the others missing the mark? Solving the neuronal cascade of death. I couldn't figure out how to leave a reply asking which of the 5 causes they are working on.
http://www.canadianstroke.ca/en/news/memorial-u-researchers-launch-post-stroke-search-and-rescue/?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+CanadianPartnershipForStrokeRecovery+%28Canadian+Partnership+for+Stroke+Recovery%29
Newfoundlanders know a lot about
search and rescue. This beautiful east-coast island has had its share
of daring seaside survival stories.
And now CPSR researchers at
Memorial University of Newfoundland are working hard to bring that grit
and determination to stroke recovery research by looking at ways to
rescue brain cells and tissue in the stormy aftermath of a stroke.
“We want to find out how to
rescue existing brain tissue before it’s too late,” says Dr. Jacqueline
Vanderluit, Associate Professor of Neurosciences. “If we can put more
tools in the hands of the clinicians, we can get better outcomes and
people can have better lives following stroke.”
In the Vanderluit lab,
researchers study blood flow in mouse brains after stroke and examine
different cell types to see how they respond to big and small strokes.
“The goal is to find ways to
manipulate the cells in order to develop new therapies to rescue brain
tissue,” doctoral student Kathleen Fifield says. “If we can find other
areas to explore by examining dysfunction at the cellular level, we can
determine the critical time point for interventions like neuroprotective
drugs.”
Identifying new drug targets for
stroke is important because existing treatments have limited time
windows and not all patients are eligible.
Dr. Vanderluit and her team are
also looking at the impact of a high-fat diet and obesity on the size
and severity of stroke. Obesity creates an inflammatory response in the
body that can worsen stroke outcomes, and obesity rates are high in
Newfoundland.
“We are looking at the impact of
a very small stroke in obese animals and specifically in the first 48
hours,” Dr. Vanderluit says. “We want to find new targets to promote
survival of brain tissue.”
Finding new and effective
treatments to save cells, repair damage, and promote stroke recovery
could be one of Newfoundland’s greatest search-and-rescue stories yet.
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