Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, August 30, 2021

Daily cocktail of four drugs cuts risk of strokes and heart attack in half

Or your doctor could have competently years ago created a protocol on all this that reduces stroke risk by 307%.  Pills vs. more natural methods, which way is your doctor going?   

Like maybe a 307%  stroke risk reduction from these 11 possibilities

Daily cocktail of four drugs cuts risk of strokes and heart attack in half

·4 min read
Aspirin in one of the four drugs in the cocktail - Jonathan Brady/PA
Aspirin in one of the four drugs in the cocktail - Jonathan Brady/PA

A daily cocktail of aspirin, statins and blood pressure pills slashes a person’s risk of a stroke in half, a study has found.

Canadian researchers analysed data from three large studies, totalling more than 18,000 people who had an average age of 63.

People were given either a regimen of placebo pills; statins alongside two blood pressure drugs; or statins, two blood pressure drugs and also aspirin.

Researchers looked at how likely a person was to suffer a cardiovascular health issue, which included heart attacks, strokes, or death from heart disease, over a five year period.

Overall, people who took all four drugs were 47 per cent less likely to suffer one of the aforementioned health issues. But in the non-aspirin cohort, the figure was just 32 per cent.

Only dementia (70,047) and Covid-19 (73,766) claimed more lives than heart diseases in England last year (55,807).

Aspirin and statins are prescribed to people who are at high risk of cardiovascular health issues, or who have a history of the conditions.

Data show that when aspirin was included in the preventative treatment, either as standalone tablets or rolled into one capsule — a so-called polypill — the risk of a person having a stroke is reduced by 51 per cent compared to someone not on medication.

The study, published in The Lancet, also found the treatment lowers the likelihood of a heart attack by 53 per cent, and of death from cardiovascular disease by 49 per cent.

In contrast, the risk reduction is just 41 per cent for stroke, 48 per cent for heart attack, and 35 per cent for cardiovascular death for people taking a polypill that does not include aspirin.

“This combination, either given separately or combined as a polypill, substantially reduces fatal and non-fatal cardiovascular disease events,” said lead author Dr Philip Joseph, associate professor of medicine at McMaster University.

“The largest effects are seen with treatments that include blood pressure lowering agents, a statin and aspirin together, which can reduce fatal and non-fatal cardiovascular events by about half.

“The benefits are consistent at different blood pressure levels, cholesterol levels and with or without diabetes, but larger benefits may occur in older people.”

A commonly prescribed statin - Finnbarr Webster / Alamy
A commonly prescribed statin - Finnbarr Webster / Alamy

Polypills are not a new concept, first being discussed around 20 years ago as a way of tackling the growing scourge of cardiovascular disease. However, there is some debate over the balance of risks and benefits.

Currently, no polypills are authorised in the UK, but they continue to win support from experts.

Professor Fausto Pinto, president of the World Heart Federation (WHF), said: “The demonstration of a low-cost approach using fixed dose combinations to reduce cardiovascular disease by about 50 per cent is extraordinary and represents a huge opportunity to tackle the condition globally, with a major potential impact on people's lives.

“The WHF has supported the use of a polypill for the last decade and these results provide robust evidence to strengthen our global advocacy strategy.”

“Although a polypill strategy might sit uncomfortably with precision medicine, there is now a substantial evidence base that such an approach is effective at reducing cardiovascular disease,” added Jonathan Mant and Richard McManus, professors of primary care at the University of Cambridge and Oxford, respectively, who were not involved in the study but wrote an accompanying comment article, also published in The Lancet.

“Guideline writers and policy makers should consider how to incorporate this evidence base into guidelines and policies.”

A separate study from The George Institute in Australia, published Sunday in the New England Journal of Medicine, found that ditching normal salt for a low-sodium alternative reduced a high-risk person’s risk of stroke by 14 per cent.(Since this is a study in China and their use of salt is completely different than the rest of the first world this is likely not transferable to other countries.)

Salt and pepper mills on a wooden table - Alamy
Salt and pepper mills on a wooden table - Alamy

“Almost everyone in the world eats more salt than they should. Switching to a salt substitute is something that everyone could do if salt substitutes were on the supermarket shelves,’’ said study author Professor Bruce Neal.

‘’Better still, while salt substitutes are a bit more expensive than regular salt, they’re still very low-cost – just a few dollars a year to make the switch.”

 

No comments:

Post a Comment