I'm not sure how this is going to help you get 100% recovered. Lots of big words though.
Memory formation in the motor cortex ipsilateral to a training hand
J. Duque
1,2
, R. Mazzocchio
1,3
, K. Stefan
1
, F. Hummel
1,4
,E. Olivier
2
and Leonardo G. Cohen
11
Human Cortical Physiology Section and StrokeNeurorehabilitation Clinic, National Institute of NeurologicalDisorders and Stroke, National Institutes of Health, Bethesda,MD 20817, USA,
2
Laboratoire de Neurophysiologie, Universite ´catholique de Louvain, B-1200 Brussels, Belgium,
3
Sezione diNeurofisiologia Clinica, Dipartimento di Scienze Neurologichee del Comportamento, Universita’ di Siena, I-53100 Siena, Italy and
4
Cortical Physiology Research Group, Department of Neurology, University Medical Center Hamburg-Eppendorf,20246 Hamburg, Germany
Cortical reorganization within the primary motor cortex (M1)contralateral to a practicing hand has been extensively investigated. The extent to which the ipsilateral M1 participates in these plastic changes is not known. Here, we evaluated the influence of unilateral hand practice on the organization of the M1 ipsilateral and contralateral to the practicing hand in healthy human subjects.Index finger movements elicited by single-pulse transcranial magnetic stimulation (TMS) delivered to each M1 were evaluated before and after practice of unilateral voluntary index fingerabduction motions. Practice increased the proportion and acceleration of TMS evoked movements in the trained direction and the amplitude of motor-evoked potentials (MEPs) in the abduction agonist first dorsal interosseous (FDI) muscle in the practicing hand and decreased the proportion and acceleration of TMS evoked abduction movements and MEP amplitudes in the abduction agonist FDI in the opposite resting hand. Our findingsindicate that unilateral hand practice specifically weakened there presentation of the practiced movement in the ipsilateral M1 to an extent proportional to the strengthening effect in the contralateral M1, a result that varied with the practicing hand’s position. These results suggest a more prominent involvement of interacting bilateral motor networks in motor memory formation and probably acquisition of unimanual motor skills than previously thought.
1,2
, R. Mazzocchio
1,3
, K. Stefan
1
, F. Hummel
1,4
,E. Olivier
2
and Leonardo G. Cohen
11
Human Cortical Physiology Section and StrokeNeurorehabilitation Clinic, National Institute of NeurologicalDisorders and Stroke, National Institutes of Health, Bethesda,MD 20817, USA,
2
Laboratoire de Neurophysiologie, Universite ´catholique de Louvain, B-1200 Brussels, Belgium,
3
Sezione diNeurofisiologia Clinica, Dipartimento di Scienze Neurologichee del Comportamento, Universita’ di Siena, I-53100 Siena, Italy and
4
Cortical Physiology Research Group, Department of Neurology, University Medical Center Hamburg-Eppendorf,20246 Hamburg, Germany
Cortical reorganization within the primary motor cortex (M1)contralateral to a practicing hand has been extensively investigated. The extent to which the ipsilateral M1 participates in these plastic changes is not known. Here, we evaluated the influence of unilateral hand practice on the organization of the M1 ipsilateral and contralateral to the practicing hand in healthy human subjects.Index finger movements elicited by single-pulse transcranial magnetic stimulation (TMS) delivered to each M1 were evaluated before and after practice of unilateral voluntary index fingerabduction motions. Practice increased the proportion and acceleration of TMS evoked movements in the trained direction and the amplitude of motor-evoked potentials (MEPs) in the abduction agonist first dorsal interosseous (FDI) muscle in the practicing hand and decreased the proportion and acceleration of TMS evoked abduction movements and MEP amplitudes in the abduction agonist FDI in the opposite resting hand. Our findingsindicate that unilateral hand practice specifically weakened there presentation of the practiced movement in the ipsilateral M1 to an extent proportional to the strengthening effect in the contralateral M1, a result that varied with the practicing hand’s position. These results suggest a more prominent involvement of interacting bilateral motor networks in motor memory formation and probably acquisition of unimanual motor skills than previously thought.
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