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“What's measured, improves.” So said management legend and author Peter F. Drucker
Clinical efficacy and safety of endovascular treatment for patients with wake-up stroke with large vessel occlusion guided by NCCT-ASPECTS
Abstract
Objective
To
evaluate the clinical efficacy and safety of 6 to 24 h endovascular
therapy (EVT) in patients with wake-up stroke (WUS) with acute large
vessel occlusion (LVO) of the anterior circulation guided by noncontrast
computed tomography-Alberta stroke program early CT score
(NCCT-ASPECTS).
Methods
Fifty-three
patients with WUS with acute LVO of the anterior circulation who were
treated at the Sir Run Run Shaw Hospital of Zhejiang Medical College
from January 2018 to March 2021 were retrospectively analyzed. The
patients were divided into NCCT-ASPECTS or CT perfusion groups. Baseline
data, perioperative data, and 90-d prognostic information were compared
between the two groups. Multivariable logistic regression analysis was
used to determine the independent factors influencing outcomes.
Results
There
were no significant differences in the good prognosis, symptomatic
intracranial hemorrhage, and mortality rates between the two groups
(P > 0.05). Multivariate logistic regression analysis showed that the
puncture-recanalization time was an independent factor for good
prognosis.
Conclusion
Based
on NCCT-ASPECTS guidance, EVT in patients with WUS for acute LVO of the
anterior circulation within 6 to 24 h may be safe and effective.
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