But what will accurately describe the chances of that aneurysm rupturing which is vastly more important to know than size.
RAPID aneurysm accurately measures aneurysm size on CT angiography compared to three-dimensional digital subtraction angiography
Abstract
Background
Cerebral
aneurysms are often identified and characterized on non-invasive CT
Angiography (CTA) images, but digital subtraction angiography (DSA) is
the gold standard for aneurysm evaluation.
Objective
We
compared cerebral aneurysm size measurements as measured from CTA
processed by a semi-automated artificial intelligence software program
(RAPID Aneurysm) and three-dimensional rotational DSA (3D-DSA).
Methods
We
performed a retrospective cohort study of consecutive patients with a
cerebral aneurysm who underwent CTA and DSA with 3D reformations. CTA
images were processed by RAPID Aneurysm to determine aneurysm height,
width, and neck width. The reference standard was aneurysm measurements
on 3D-DSA as measured by two neurointerventionalists. Both readers were
blinded to RAPID Aneurysm measurements. Correlation and bias between
these measurements were determined.
Results
Results
from 50 patients with 50 aneurysms were compared. 32 patients (64%)
were female. Median age was 65 (IQR: 56.25–71.75). 37 patients (74%)
presented with ruptured aneurysms. The aneurysms represented a range of
aneurysm sizes (1.9–33.3 mm; IQR 3.6–7.2 mm). RAPID Aneurysm size
measurements showed excellent correlation and low bias (correlation,
mean difference) when compared to the reference standard for aneurysm
height (0.98, −0.9 mm), width (0.98, 0.1 mm), and neck width (0.94, 1.1
mm). The inter-reader comparison between the two neurointerventionalists
was similarly excellent for aneurysm height (0.97, −0.4 mm), width
(0.98, −0.2 mm), and neck width (0.89, 0.8 mm).
Conclusion
RAPID
Aneurysm measurement of cerebral aneurysm height, width, and neck width
on CTA is strongly correlated to expert neurointerventionalist
measurements on 3D-DSA.
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