Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, March 12, 2025

Comparison of Five Rehabilitation Interventions for Acute Ischemic Stroke: A Randomized Trial

 You can conclude what this means yourself.

Comparison of Five Rehabilitation Interventions for Acute Ischemic Stroke: A Randomized Trial


                                 by 1,2,3,4,5,*, 1,2,3, 1, 1, 3, 3, 3, 6,7,*, 8 and 1,9,10,11
1
Somogy County Kaposi Mór Teaching Hospital, H-7400 Kaposvár, Hungary
2
Faculty of Health Sciences, Doctoral School of Health Sciences, University of Pécs, H-7621 Pécs, Hungary
3
Digital Development Center, Széchenyi István University, H-9000 Győr, Hungary
4
Department of Otorhinolaryngology-Head and Neck Surgery, University of Pécs Medical School, H-7621 Pécs, Hungary
5
Hungarian Academy of Science, H-1011 Budapest, Hungary
6
University Research and Innovation Center (EKIK), Óbuda University, Bécsi út. 96/b, H-1034 Budapest, Hungary
7
John von Neumann Faculty of Informatics, Óbuda University, H-1034 Budapest, Hungary
8
Faculty of Physical Education and Sport, Charles University, 162 52 Prague, Czech Republic
9
Department of Kinesiology, Hungarian University of Sports Science, H-1123 Budapest, Hungary
10
Department of Sport Biology, Institute of Sport Sciences and Physical Education, University of Pécs, H-7624 Pécs, Hungary
 
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*
Authors to whom correspondence should be addressed.
J. Clin. Med. 2025, 14(5), 1648; https://doi.org/10.3390/jcm14051648
Submission received: 7 December 2024 / Revised: 7 February 2025 / Accepted: 22 February 2025 / Published: 28 February 2025
(This article belongs to the Special Issue Acute Ischemic Stroke: Current Status and Future Challenges)
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Versions Notes

Abstract

Background: Comparative efficacy of rehabilitation interventions in persons with acute ischemic stroke (PwS) is limited. This randomized trial assessed the immediate and lasting effects of five interventions on clinical and mobility outcomes in 75 PwS. 

Methods: Five days after stroke, 75 PwS were randomized into five groups: physical therapy (CON, standard care, once daily); walking with a soft robotic exoskeleton (ROB, once daily); agility exergaming once (EXE1, once daily) or twice daily (EXE2, twice daily); and combined EXE1+ROB in two daily sessions. Interventions were performed 5 days per week for 3 weeks. Outcomes were assessed at baseline, post-intervention, and after 5 weeks of detraining. 

Results: Modified Rankin Scale (primary outcome) and Barthel Index showed no changes. EXE1, EXE2, ROB, and EXE1+ROB outperformed standard care (CON) in five secondary outcomes (Berg balance scale, 10m walking speed, 6-min walk test with/without robot, standing balance), with effects sustained after 5 weeks. Dose effects (EXE1 vs. EXE2) were minimal, while EXE1+ROB showed additive effects in 6-min walk tests. 

Conclusions: These novel comparative data expand evidence-based options for therapists to design individualized rehabilitation plans for PwS. Further confirmation is needed.
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