I don't think they have cause and effect down yet. Ask your doctor.
http://www.medpagetoday.com/Cardiology/Strokes/32382
Patients with age-related macular degeneration appear to be at risk for both ischemic and hemorrhagic stroke, researchers found.
Through an average follow-up of 13 years, middle-age individuals with
the eye condition had a higher rate of any stroke (7.6% versus 4.9%),
according to M. Kamran Ikram, MD, of the Singapore Eye Research Institute, and colleagues.
The difference was consistent for both ischemic stroke (6.4% versus
4.4%) and intracerebral hemorrhage (1.2% versus 0.4%), the researchers
reported online in Stroke: Journal of the American Heart Association.
"These data provide further insight into common pathophysiological
processes between age-related macular degeneration and stroke subtypes,"
they wrote.
Previous studies have examined the relationship between age-related macular degeneration and stroke, with some showing a positive association and others showing no correlation.
The current study included 12,216 middle-age individuals (ages 45 to
64) who had retinal photographs taken at the third examination visit of
the Atherosclerosis Risk in Communities (ARIC) study.
Overall, 591 participants (4.9%) were diagnosed with age-related
macular degeneration. Of those, 576 had early disease, defined as the
presence of either soft drusen alone, retinal pigment epithelial
depigmentation alone, or a combination of soft drusen with increased
retinal pigment and/or retinal pigment epithelial depigmentation.
The rest had late disease, defined as the presence of exudative age-related macular degeneration or pure geographic atrophy.
Through follow-up, 619 of the participants (5.1%) had a stroke,
including 548 cerebral infarctions, 57 intracerebral hemorrhages, and 14
subarachnoid hemorrhages.
Those with any age-related macular degeneration were about 50% more
likely to have a stroke during follow-up (HR 1.51, 95% CI 1.11 to 2.06)
after adjustment for age, sex, race, field center, mean arterial blood
pressure, antihypertensive medications, fasting glucose, total
cholesterol, HDL cholesterol, triglyceride levels, body mass index,
atrial fibrillation, white blood cell count, cigarette smoking, and
alcohol consumption.
The relationship was stronger for intracerebral hemorrhage (HR 2.64,
95% CI 1.18 to 5.87) than for ischemic stroke (HR 1.42, 95% CI 1.01 to
1.99).
"Recently, antivascular endothelial growth factor agents used in the
treatment of neovascular age-related macular degeneration have been
suggested to increase the risk of intracerebral hemorrhage," the authors
noted. "Based on our findings, it appears that patients with [the eye
disease] may already be at an increased risk of intracerebral hemorrhage
and, thus, antivascular endothelial growth factor therapy could
potentially increase this risk further."
"However," they added, "additional studies are needed to confirm this
potential side effect of antivascular endothelial growth factor
agents."
They acknowledged some limitations of the study, including the fact
that the technique used for taking retinal photographs makes grading
age-related macular degeneration more variable, the use of pictures from
only one eye for each participant, and the low number of patients with
late age-related macular degeneration.
Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 29,112 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
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