So this is the belief in 'good' neurons. Is it helpful in more than memory neurons? full article at the link.
http://www.scientificamerican.com/article.cfm?id=keeping-up-with-the-neurons
Neurons, or nerve cells, each have a pair of projections—the axon and
the dendrite, which transmit and receive impulses, respectively. The
dendrite, a treelike structure, has several branches dotted with
hundreds synaptic receiving terminals called "spines," each connected to
the axons of scores of other neurons. When one of these spines receives
stimulation (through the synapse it creates with another cell's axonal
projection), the spine expands into the synapse, strengthening the link
between its neuron and the other cell. This process of enhanced
communication through a synapse is called long-term potentiation (LTP) and is thought to be the basis of learning.
Previous attempts to identify this process were stymied by inexact
methods. Researchers primarily used electrical impulses, which do not
allow for good spatial observation. Svoboda and study co-author
Christopher Harvey, a graduate student in Svoboda's lab, used a more
precise technique. They attached a light-absorbing chemical group to the
neurotransmitter glutamate (an excitatory chemical messenger in the
brain) at a particular synapse in a slice of a rat's hippocampus, the
brain region responsible for short-term memory. When they trained a
laser on the glutamate, it was freed from its light-absorbing molecular
captor and thereby able to resume its function; it went to the dendritic
spine in the synapse, allowing ions to enter the cell and an electrical
signal to be generated.
As a result of this stimulation, the spine stretched farther into the
synapse. Researchers did not find any evidence that neighboring spines
had also expanded, but they did find that it took less stimulation—only
20 percent of the original prodding—to prompt any of the 20 spines
within 10 microns (around four ten-thousandths of an inch) to undergo
LTP. This effect appeared to last for five to 10 minutes, the scientists
report.
Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 29,286 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke. DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
Wednesday, April 25, 2012
Signaling Neurons Make Neighbor Cells "Want In"
Labels:
dendritic branching,
glutamate,
LTP,
neuroplasticity,
rats,
synapses
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