Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, September 3, 2012

Statins linked with development of cataracts

Another discussion point with your doctor, if you are keeping track I'll be indexing all of statin side effects under that name  for your ease of doctor questioning.
http://www.theheart.org/article/1434435.do?utm_medium=email&utm_source=20120903_TopTen&utm_campaign=newsletter
Statin users are more than 50% likelier to develop age-related cataracts, according to the results of a new study [1]. And type 2 diabetics who use statins are at even greater risk of cataracts, report investigators.
"The bioplausibility of these results lies in the fact that the crystalline lens membrane requires high cholesterol for proper epithelial cell development and lens transparency," write Dr Carolyn Machan (University of Waterloo, ON) and colleagues in the August 2012 issue of Optometry and Vision Science. "Increased cataract formation has been seen in both animals and humans with hereditary cholesterol deficiency, and the risk exists that statins can inhibit cholesterol biosynthesis in the human lens."
Asked to comment on the paper for heartwire, Dr Richard Karas (Tufts University School of Medicine, Boston, MA), called the findings "an interesting observation [that] isn't alarmist." There is, he says, a "suggestion" here that statins may increase the risk of cataracts, but this visual problem eventually afflicts everyone of a certain age anyhow, he says, adding that further study of this association will be required.

Waterloo Eye Study includes almost 6500 patients
The analysis included 6397 patients with and without diabetes. As the researchers note, diabetes is a risk factor for the development of cataracts, leading the group to analyze the prevalence of cataracts among patients with diabetes taking statins (n=452) and the prevalence among those taking statins but without diabetes (n=5884). The mean age of patients with diabetes was 14 years older than those without diabetes and included a slightly higher proportion of female subjects. The prevalence of statin use in patients 38 years of age and older was 56% for those with type 2 diabetes and 16% for those without diabetes.
In the study, known as the Waterloo Eye Study, diabetes was associated with an 86% higher risk of developing cataracts (odds ratio [OR] 1.86; 95% CI 1.34-2.59) across the lifespan after researchers controlled for multiple variables, including age, female sex, smoking, and blood pressure. A diagnosis of diabetes was also associated with an increased risk of different subtypes of cataracts: an 84% greater risk of nuclear sclerosis, a 38% higher risk of cortical cataract, and a 52% rise in posterior subcapsular cataract
Statin use was also associated with a significantly increased risk of developing age-related cataracts (OR 1.57; 95% CI 1.15-2.13) and some subtypes, including a 48% higher risk of nuclear sclerosis and a 48% rise in posterior subcapsular cataract but no increased risk of cortical cataract.
In an analysis of cataract prevalence among patients with and without diabetes taking statins, Machan and colleagues found that the prevalence of cataract increased at a faster rate in patients with diabetes who used statins. "Similar prevalence levels were seen in patients with diabetes who did not use statins and in patients without diabetes who did use statins," according to the researchers. "The prevalence of cataract increased at the slowest rate in patients without diabetes who did not use statins."

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