But will neurogenesis in the hippocampus offset these declines?
http://www.news-medical.net/news/20120910/Stroke-patients-on-a-downhill-memory-slope.aspx
The large memory declines associated with acute stroke are part of a long-term downward trajectory, show findings from the Health and Retirement Study (HRS).
Even before the event, HRS participants who had stroke had significantly steeper memory declines than those who did not.
The
HRS participants did an immediate- and delayed-recall memory test every
2 years, which revealed memory declines of an average 0.143 points per
year among the 1574 participants who went on to have a stroke. By
contrast, the decline was just 0.101 points per year among the 15,766
who remained stroke-free during up to 10 years of follow up.
Memory
differences between participants who did and did not have a stroke were
apparent up to 4 years before onset. The differences persisted after
accounting for variables including age, gender, and age at stroke onset.
"Prestroke memory decline is most likely an early sign of cerebrovascular disease," M Maria Glymour and team, from the Harvard School of Public Health in Boston, Massachusetts, USA, write in Stroke.
"However,
it is also plausible that lower memory performance increases
vulnerability to clinically manifest stroke. Individuals with very high
memory scores may have better cognitive reserve and may be able to
sustain an acute ischemic event without severe clinical manifestations."
They note that this difference "has important clinical implications and therefore merits further exploration."
The
prestroke rate of memory decline was particularly steep among the 385
people who did not survive their stroke. At 0.212 points per year, this
was a significantly steeper decline than that seen among stroke
survivors.
"These individuals may have particularly severe
underlying cerebrovascular disease that causes very rapid cognitive
declines culminating in fatal stroke,
or the prestroke cognitive declines may be attributable to causes other
than cerebrovascular disease but may render the patient frail or
unusually vulnerable to death as a result of the stroke," Glymour et al
suggest.
Stroke caused a large decrease in memory performance, of
0.369 points, equivalent to 3.7 years of age-related memory decline
among stroke-free participants. But after stroke, memory in stroke survivors continued to decline at a similar rate to that before stroke, at 0.142 points per year.
"This
finding may indicate that cerebrovascular risk factors are not
adequately controlled after stroke diagnosis, or that acute stroke
presages an ongoing, cascading process of neurological injury," say the
researchers.
Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 29,112 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
Saturday, September 29, 2012
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