http://link.springer.com/article/10.1007%2Fs100720070114?LI=true
Abstract
The objectives of
this study were to investigate the efficacy of bromocriptine (BR)
combined with speech therapy (ST) to improve a late recovery in
non-fluent aphasic stroke patients. We performed a double-blind study
with high dosage of BR, prescribed according to a dose-escalating
protocol, comprehensive of clinical data, relatives' impression, and
language evaluations. The study was divided into the following phases:
t-0, inclusion; t-30, language re-test to evaluate the stability of
aphasia; t-90, placebo (PL) and ST; t-150, BR and ST; t-210, BR; t-270,
wash-out. With respect to the baseline assessment, a significant
improvement was observed in the following tests: dictation (F, 4.8; p < .04), reading-comprehension (F, 8.1; p < .0003), repetition (F, 3.8; p < .01) and verbal latency (F, 4.9; p < .01). High dosage of BR promoted a late recovery in stable chronic
non-fluent aphasia and this improvement was enhanced by combination
with ST.
It sounded good until I read that 5 of the 11 people dropped out of the study due to side effects like seizures and atrial fibrilation.
ReplyDeleteThats why we need free access to research, I'm not paying $30 for each of the dozens of reports I'd like to read each day.
ReplyDelete