Deans' stroke musings: Omega-3 fatty acids and traumatic neurological injury: from neuroprotection to neuroplasticity?

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, November 25, 2013

Omega-3 fatty acids and traumatic neurological injury: from neuroprotection to neuroplasticity?

I know this says this needs review before clinical translation but I'm going to insist on this because of these already; Ask your doctor, whats the downside?
Fish oil.
either by injection
http://oc1dean.blogspot.com/2013/03/fish-oil-may-help-stroke-patients.html
or a feeding tube
http://oc1dean.blogspot.com/2012/10/fish-oil-for-brain-injuries-tbi.html

http://www.sciencedirect.com/science/article/pii/S0166223613001987

Centre for Neuroscience and Trauma, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK

Highlights

•: Evidence for positive effects of omega-3 polyunsaturated fatty acids (PUFA) in CNS.
•: Omega-3 PUFAs potential treatment for spinal cord or traumatic brain injury.
•: Omega-3 PUFA delivery after or dietary exposure prior to injury improves outcomes.
•: Neuroprotective effects of omega-3 PUFAs likely mediated via multiple pathways.
•: Understanding role of omega-3 PUFAs in neuroplasticity critical next step.

Omega-3 polyunsaturated fatty acids (PUFAs) are compounds that have a structural role in the nervous system and are essential for neurodevelopment. Results obtained with docosahexaenoic acid and eicosapentaenoic acid show therapeutic potential in neurotrauma. Traumatic brain injury (TBI) and spinal cord injury (SCI) can lead to major disability and have a significant socioeconomic cost. Thus, there is an unmet need for acute neuroprotection and for treatments that promote neuroregeneration. Acute administration of omega-3 PUFAs after injury and dietary exposure before or after injury improve neurological outcomes in experimental SCI and TBI. The mechanisms involved include decreased neuroinflammation and oxidative stress, neurotrophic support, and activation of cell survival pathways. This review raises questions that must be addressed before successful clinical translation.