Deans' stroke musings: Underweight seniors may have an additional risk of developing Alzheimer’s disease

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, August 10, 2016

Underweight seniors may have an additional risk of developing Alzheimer’s disease

What weight range should you be in post-stroke to not get dementia/Alzheimers? What is your doctors protocol on that?
1. A documented 33% dementia chance post-stroke from an Australian study? May 2012.
2. Then this study came out and seems to have a range from 17-66%. December 2013.
3. A 20% chance in this research. July 2013.

https://consumer.healthday.com/cognitive-health-information-26/alzheimer-s-news-20/weight-alzheimer-s-jad-bwh-mgh-release-batch-2804-713539.html?WT.mc_id=enews2016_08_10&utm_source=enews-aff-99&utm_medium=email&utm_campaign=enews-2016-08-10
Having a lower weight may increase older adults' risk of the memory-robbing disorder Alzheimer's disease, new research suggests.
The study included 280 healthy people aged 62 to 90 with normal mental function. The participants underwent physical exams, genetic testing and brain scans.
According to the researchers from Brigham and Women's Hospital and Massachusetts General Hospital in Boston, there was a link between lower body weight and more extensive deposits of Alzheimer's-related beta-amyloid protein in the brain.
This link was particularly strong in people with the APOE4 gene variant, which is known to increase the risk of Alzheimer's, the study authors reported.
"Elevated cortical amyloid is believed to be the first stage of the preclinical form of Alzheimer's disease, so our findings suggest that individuals who are underweight late in life may be at greater risk for this disease," senior study author Dr. Gad Marshall said in a joint hospital news release. Marshall is a neurologist at Brigham and Women's and Mass General, and is also an assistant professor of neurology at Harvard Medical School.
"Finding this association with a strong marker of Alzheimer's disease risk reinforces the idea that being underweight as you get older may not be a good thing when it comes to your brain health," he added.
The association seen in the study doesn't prove a cause-and-effect relationship. Further research is needed to learn more about the connection between lower body weight and increased amyloid levels, the investigators noted.
"A likely explanation for the association is that low BMI (body mass index) is an indicator for frailty -- a syndrome involving reduced weight, slower movement and loss of strength that is known to be associated with Alzheimer's risk," Marshall said.
The study was published Aug. 3 in the Journal of Alzheimer's Disease.
More information
The U.S. National Institute on Aging has more about Alzheimer's disease.

SOURCE: Brigham and Women's Hospital, Massachusetts General Hospital, news release, Aug. 2, 2016