Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Saturday, June 10, 2017

CONTRALATERAL HEMISPHERIC BRAIN ATROPHY AFTER HEMORRHAGIC STROKE

An abstract from the European Stroke Organisation Conference 2017.  You are completely on your own to find out what can be done about it.
S. Joo1
1Chonnam National University Hospital, Gwangju, Republic of Korea
Background and Aims: Brain atrophy occurs on the ipsilateral hemisphere in patients with intracerebralhematoma (ICH). This study aimed to investigate contralateral hemispheric volume change in patients with ICH and related factors.
Method: In surgically treated 312 patients with ICH between January 2010 and December 2015, 44 patients were included in this study. We measured contralateral hemispheric brain area in three different level of axial brain computed tomography (CT) images using CT based software. Proportion of contralateral hemispheric parenchyma to intracranial area was measured to adjust individual difference in head size. We analyzed relationship between various possible factors and the contralateral hemispheric volume change.
Results: The median follow up interval between preoperative and postoperative brain CT was 89.5 days (range, 30–180). The average volume ratios of preoperative and postoperative contralateral hemispheric parenchyma were 92.3% vs. 88.8%, 90.3% vs. 85.3% and 86.9% vs. 82.5% in the level of third ventricle, septum pellucidum and lateral ventricle, respectively. The declination of contralateral parenchymal volume ratio had all statistical significance in three different levels through paired t-test (p-value <0.001). In various possible factors, presence of intraventricular hematoma (IVH) was the most significant factor for contralateral parenchymal volume ratio decrease (p-value = 0.006). Glasgow coma scale (GCS) on arrival and smoking were independent factors in multivariate analysis (p-value = 0.016, 0.039).
Conclusion: Contralateral parenchymal volume ratio was decreased significantly on the 3 months follow up brain CT scan. The mechanism of this morphological change might be associated with neuroinflammation and diaschisis.

No comments:

Post a Comment