Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, October 17, 2017

Blood pressure medication does not completely restore vascular function

How big a problem is this? Solution?
http://www.alphagalileo.org/ViewItem.aspx?ItemId=179959&CultureCode=en
16 October 2017 Lancaster University
Treatments for high blood pressure do not totally reverse its damaging effects on the vascular rhythms that help circulation of the blood say researchers.
The World Health Organisation says hypertension affects about 40% of those aged over 25 and is a major risk factor for heart disease, stroke and kidney failure.
An interdisciplinary group of scientists from Lancaster University found that conventional medication aimed at reducing high blood pressure restored normal vascular rhythms only in the largest blood vessels but not the smallest ones.
Professor Aneta Stefanovska said: “It is clear that current anti-hypertensive treatments, while successfully controlling blood pressure, do not restore microvascular function.”
Based on a networks physiology approach, the researchers compared a group aged in their twenties and two older groups aged around 70 – one with no history of hypertension and the other taking medications for high blood pressure.
In the older group being treated for high blood pressure the drug treatment restored normal function at the level of arterioles and larger vessels.
But when the researchers studied the nonlinear dynamical properties of the smallest blood vessels in the body, they found differences between the two older groups.
“Specifically, current hypertensive treatment did not fully restore the coherence or the strength of coupling between oscillations in the heart rate, respiration, and vascular rhythms (vasomotion).
“These are thought to be important in the efficient and adaptive behaviour of the cardiovascular system. Indeed, one aspect of ageing is the progressive physiological weakening of these links that keep the cardiovascular system reactive and functional.
 “The results have not only confirmed previous observations of progressive impairment with age of the underlying mechanisms of coordination between cardiac and microvascular activity, but for the first time have revealed that these effects are exacerbated in hypertension.
“Current antihypertensive treatment is evidently unable to correct this dysfunction. Our novel multiscale analysis methods could help in optimising future drug developments that would benefit from taking microvascular function into account.”
https://www.frontiersin.org/articles/10.3389/fphys.2017.00749/full


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