Why eat three bananas a day? April 2012
The Northern Manhattan Study
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Abstract
Background and Purpose—There
is growing evidence that increased dietary sodium (Na) intake increases
the risk of vascular diseases, including stroke, at least in part via
an increase in blood pressure. Higher dietary potassium (K), seen with
increased intake of fruits and vegetables, is associated with lower
blood pressure. The goal of this study was to determine the association
of a dietary Na:K with risk of stroke in a multiethnic urban population.
Methods—Stroke-free
participants from the Northern Manhattan Study, a population-based
cohort study of stroke incidence, were followed-up for incident stroke.
Baseline food frequency questionnaires were analyzed for Na and K
intake. We estimated the hazard ratios and 95% confidence intervals for
the association of Na:K with incident total stroke using multivariable
Cox proportional hazards models.
Results—Among
2570 participants with dietary data (mean age, 69±10 years; 64% women;
21% white; 55% Hispanic; 24% black), the mean Na:K ratio was 1.22±0.43.
Over a mean follow-up of 12 years, there were 274 strokes. In adjusted
models, a higher Na:K ratio was associated with increased risk for
stroke (hazard ratio, 1.6; 95% confidence interval, 1.2–2.1) and
specifically ischemic stroke (hazard ratio, 1.6; 95% confidence
interval, 1.2–2.1).
Conclusions—Na:K
intake is an independent predictor of stroke risk. Further studies are
required to understand the joint effect of Na and K intake on risk of
cardiovascular disease.
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