So you described a problem but DID NOTHING to solve it. Useless.
Poor collateral flow with severe hypoperfusion explains worse outcome in acute stroke patients with atrial fibrillation
Abstract
Background:
Atrial Fibrillation (AF) is associated with poorer functional outcomes
in acute stroke patients. It has been hypothesized that this is due to
poor collateral recruitment.
Aims: This study aimed to investigate the relationship between AF and collaterals with outcome in thrombectomy patients.
Methods:
This retrospective cohort study identified 1036 acute ischemic patients
from the INternational Stroke Perfusion Imaging REgistry. The cohort
was divided into two groups: 432 with AF and 604 without AF. Patients
were stratified by collateral grades as good, moderate, and poor. Within
each collateral grade, the prediction of AF vs. No AF for good outcome
(3-month modified Rankin Scale of 0-2) was determined. Then, within each
collateral grade, perfusion was compared between those with and AF and
without AF.
Results:
AF was negatively
associated with good outcome in patients with poor collaterals (26.7%
vs. 51.2% for AF vs. No AF, odds ratio=0.32 [95% CI 0.22, 0.50],
p<0.001), but not in patients with good (50.9% vs 58.1% for AF vs. No
AF, odds ratio=0.75 [0.46, 1.23], p=0.249) or moderate collaterals
(43.6% vs 50.9% for AF vs. No AF, odds ratio=0.75 [0.47, 1.18],
p=0.214). AF was associated with severe hypoperfusion only in patients
with poor collateral flow (54.0 vs. 35.5 ml for AF vs. No AF,
p<0.001).
Conclusions:
AF-related stroke is associated with more severe hypoperfusion and worse outcome in those with poor collaterals.
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