Deans' stroke musings: High and Low HDL Cholesterol Levels Linked to Dementia Risk

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, October 20, 2023

High and Low HDL Cholesterol Levels Linked to Dementia Risk

I have no clue what my levels are and I'm not worried about them.

Because of this:

Dementia prevention 19 ways per Dean.

Here’s What Really Matters in Preventing Dementia. It’s Not All Brain Teasers and Crosswords.

High and Low HDL Cholesterol Levels Linked to Dementia Risk

TOPLINE:

High and low levels of high-density lipoprotein cholesterol (HDL-C) but not levels of low-density lipoprotein cholesterol (LDL-C) are associated with an increased risk for dementia in older adults, a new study found.

METHODOLOGY:

Electronic health record and survey data on 184,367 Kaiser Permanente Northern California participants (median age 69.5 years) with no history of dementia were taken.
Cholesterol levels were measured within 2 years of survey completion.

TAKEAWAY:

There were 25,214 incident cases of dementia reported over an average follow-up of 8.77 years.
Dementia risk was significantly higher in people with low HDL-C (11-41 mg/dL; adjusted hazard ratio [aHR], 1.07; 95% CI, 1.03-1.11) and high HDL-C (> 65 mg/dL; aHR, 1.15; 95% CI, 1.11-1.20).
The study demonstrates an association between low and high levels of "good" cholesterol but not a causal link.
There was no significant association between LDL-C and dementia risk.

IN PRACTICE:

"These results support the conclusion that some lipoproteins may be modifiable risk factors for dementia, even in late life," the authors write.

SOURCE:

The study was conducted by Erin L. Ferguson, MPH, Department of Epidemiology & Biostatistics, University of California, San Francisco, California, and was funded by the National Institutes of Health. It was published online October 4, 2023 in Neurology.