Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, November 20, 2024

Finger-Prick Test Brings Alzheimer’s Detection Closer to Everyone

 With this your competent? doctor can implement the EXACT DEMENTIA PROTOCOLS as soon as this diagnosis comes in. At least if you have a competent doctor! Do you have one? NO? RUN AWAY!

 With your chances of getting dementia post stroke, you need prevention solutions. YOUR DOCTOR IS RESPONSIBLE FOR PREVENTING THIS!

1. A documented 33% dementia chance post-stroke from an Australian study?   May 2012.

2. Then this study came out and seems to have a range from 17-66%. December 2013.`    

3. A 20% chance in this research.   July 2013.

4. Dementia Risk Doubled in Patients Following Stroke September 2018 

The latest here:

Finger-Prick Test Brings Alzheimer’s Detection Closer to Everyone

Summary: A new Alzheimer’s test collects just a few drops of blood from a finger prick, which can be mailed to a lab for analysis. The test measures biomarkers like pTau217 and has shown similar accuracy to traditional venous blood sampling.

Unlike conventional methods, this approach doesn’t require cold-chain transportation, making it highly accessible for regions with limited infrastructure. With early detection critical for treatments like lecanemab, this test could revolutionize Alzheimer’s diagnosis and research accessibility worldwide.

Key Facts:

  • The finger-prick test for Alzheimer’s biomarkers is nearly as accurate as venous sampling.
  • Blood samples are mailed to labs without requiring specialized transportation.
  • Early detection is key for effective treatments and expanding global research.

Source: University of Gothenburgh

A quick finger prick and a few drops of blood on a card that can be sent in regular mail. This approach could soon make Alzheimer’s testing much more accessible worldwide. A European study led by researchers at the University of Gothenburg, Sweden, is paving the way for this method.

The biomarkers measured in this test have been developed over a long period and have shown strong performance – initially in cerebrospinal fluid, then in venous blood samples, and now in blood from superficial vessels in the finger.

This shows a researcher holding a card with blood on it, a brain is in the background.
The test could potentially be implemented within a few years. Credit: Neuroscience News

The new test involves collecting one or two drops of blood from a finger prick onto a special card, which immediately separates blood cells from the plasma. After approximately 15 minutes, once the card has dried, it is sent by regular mail to a laboratory, where modern high-sensitivity techniques are used to analyze it.

As effective as venous blood sampling

The current study includes capillary blood samples from 203 people who underwent the finger prick test at one of five memory clinics in Europe. The simple test kit was then mailed to the neurochemistry department at the University of Gothenburg, where established biomarkers for Alzheimer’s, such as pTau217, were analyzed.

The results were presented at the CTAD (Clinical Trials on Alzheimer’s Disease) conference in Madrid, Spain, on October 30, 2024, by Hanna Huber, a researcher at the University of Gothenburg’s Sahlgrenska Academy:

“The simple capillary blood test works almost as well as venous samples, but unlike traditional blood tests, this new test does not require transport on dry ice. This could significantly increase accessibility to Alzheimer’s testing in countries and regions lacking the infrastructure needed for high-sensitivity analyses,” says Hanna Huber.

The test could potentially be implemented within a few years. A new European study is already underway to examine whether the test can be self-administered, allowing individuals to prick their own finger and mail the sample to a lab without the need for healthcare personnel.

Early detection

The test comes at a fitting time alongside the development of Alzheimer’s treatments, with the drug lecanemab already approved in numerous countries outside the EU. These treatments require early disease detection to be effective.

The test opens up possibilities for new research breakthroughs on Alzheimer’s disease, including its genetic profile and its prevalence across global populations. However, researchers emphasize that the test is not intended for general screening of the population.

The World Health Organization (WHO) currently advises against general screening for Alzheimer’s disease, as treatment options have historically been limited, making such screening ethically unsubstantiated.

The study utilizes the blood collection cards Capitainer®SEP10 and Telimmune.

About this Alzheimer’s disease research news

Author: Margareta Gustafsson Kubista
Source: University of Gothenburg
Contact: Margareta Gustafsson Kubista – University of Gothenburg
Image: The image is credited to Neuroscience News

Original Research: The findings were presented at CTAD (Clinical Trials on Alzheimer’s Disease)

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