Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, November 14, 2024

Delivery of Neuroregenerative Proteins to the Brain for Treatments of Neurodegenerative Brain Diseases

Your competent? doctor is responsible for initiating research into delivering these to stroke patient brains! If your doctor doesn't do that; YOU DON'T HAVE A FUNCTIONING STROKE DOCTOR! RUN AWAY! 

This is what LIF is: LIF: Not Just a Leukemia Inhibitory Factor 

  • IGF-1 (13 posts to March 2014)
  • BDNF (179 posts to April 2011)
  • NGF (15 posts to November 2012)


    • The latest here:

    Delivery of Neuroregenerative Proteins to the Brain for Treatments of Neurodegenerative Brain Diseases

    by ,
     † and *
    Department of Pharmaceutical Chemistry, School of Pharmacy, The University of Kansas, 2095 Constant Avenue, Lawrence, KS 66047, USA
    *
    Author to whom correspondence should be addressed.
    †
    Current Address: Department of Biological Analytical Research and Development, Merck Inc., 126 E. Lincoln Ave., Rahway, NJ 07065, USA.
    Life 2024, 14(11), 1456; https://doi.org/10.3390/life14111456
    Submission received: 21 September 2024 / Revised: 1 November 2024 / Accepted: 7 November 2024 / Published: 10 November 2024
    (This article belongs to the Section Medical Research)
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    Versions Notes

    Abstract

    Neurodegenerative brain diseases such as Alzheimer’s disease (AD), multiple sclerosis (MS), and Parkinson’s disease (PD) are difficult to treat. Unfortunately, many therapeutic agents for neurodegenerative disease only halt the progression of these diseases and do not reverse neuronal damage. There is a demand for finding solutions to reverse neuronal damage in the central nervous system (CNS) of patients with neurodegenerative brain diseases. Therefore, the purpose of this review is to discuss the potential for therapeutic agents like specific neurotrophic and growth factors in promoting CNS neuroregeneration in brain diseases. We discuss how BDNF, NGF, IGF-1, and LIF could potentially be used for the treatment of brain diseases. The molecule’s different mechanisms of action in stimulating neuroregeneration and methods to analyze their efficacy are described. Methods that can be utilized to deliver these proteins to the brain are also discussed.
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