Deans' stroke musings: The impact of low plasma atherosclerosis index on hemorrhagic transformation after endovascular treatment of large artery atherosclerotic stroke

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, December 2, 2025

The impact of low plasma atherosclerosis index on hemorrhagic transformation after endovascular treatment of large artery atherosclerotic stroke

You mention NOTHING ON HOW TO STOP HEMORRHAGIC TRANSFORMATION; so completely fucking useless!

The impact of low plasma atherosclerosis index on hemorrhagic transformation after endovascular treatment of large artery atherosclerotic stroke

Jianqiang Hu¹^†

Mingqing Cheng¹^†

Shuyu Ma¹

Jiawei Zhang¹

Xin Miao¹

Tingting Liu²

Kefangyuan Zheng¹

Yalan Fang³^*

Jin Zhang²^*

¹Clinical College, Shanxi Medical University, Taiyuan, China
²Department of Neurology, First Hospital of Shanxi Medical University, Taiyuan, China
³Department of Neurology, Second Hospital of Shanxi Medical University, Taiyuan, China

Objective: The plasma Atherosclerosis Index (AIP) reflects lipid metabolism, but its relationship with hemorrhagic transformation (HT) after endovascular treatment (EVT) in large artery atherosclerotic stroke (LAA) is unclear. This study aims to assess AIP’s potential in predicting HT occurrence.

Methods: This retrospective study analyzed 467 LAA patients. The patients were grouped based on infarct volume (small, moderate, and large). Univariate and multivariate logistic regression models evaluated the relationship between AIP levels and HT risk. Additionally, we analyzed hemorrhagic infarction (HI), parenchymal hemorrhage (PH) and symptomatic hemorrhagic transformation (sHT) to evaluate the relationship between AIP and the risk of them.

Results: Among the 467 patients, 199 experienced HT after EVT. After adjusting for confounders in the multivariate logistic regression model, lower AIP (OR = 0.20, p = 0.001) was significantly associated with an increased risk of HT. Subgroup analysis revealed that in the small infarct volume group, lower AIP (OR = 0.11, p = 0.012) was significantly associated with the risk of HT. AIP was also significantly associated with the risk of HI (OR = 0.12, p = 0.003) and sHT (OR = 0.11, p = 0.002) in HT.

Conclusion: Lower AIP levels are an independent risk factor for HT after EVT in LAA patients, especially in the small infarct volume group. Moreover, AIP is associated with HI and sHT.