Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, November 29, 2025

Can Personality Protect Against Cognitive Decline in Aging? A 25 year Longitudinal Study of Experiential Openness, Neuroplasticity and Cognitive Aging David J Sperbeck North Star Behavioral Health Hospital, 2530 Debarr Road, Anchorage, Alaska 99508, US

I'm very good at all of this. It's probably why I flourished after moving to Michigan knowing nobody there.


Experiential openness, or "Openness to Experience," is a personality trait defined by a person's willingness to embrace new experiences, explore new ideas, and be curious about the unknown. This trait is characterized by creativity, imagination, intellectual curiosity, and a tolerance for ambiguity, and it is one of the five core traits in the widely recognized Five-Factor Model of personality (OCEAN). People with high experiential openness are often innovative, adaptable, and flexible, while those with low scores prefer familiarity and routine.

 Can Personality Protect Against Cognitive Decline in Aging? 

 ABSTRACT 
 Studies of neurocognition across the lifespan have demonstrated gradual declines among healthy adults in the domains of memory, problem-solving, sensory processing, executive functioning, and processing speed. However, recent advances in the field of personality neuroscience have discovered significant differences between and within individuals’ capacity to compensate for these differences, ultimately altering the degree and magnitude of neurocognitive decline in the aging process. Experiential Openness (EO), first proposed by Costa and McCrae in their five-factor model of personality has been found to be positively related to preserved autobiographical memory recall and reminiscing activity. Additionally, Ihle, Zuber, Gouveia, et. al. found that EO adults engaged in more leisure time activities which served to mediate smaller cognitive declines in executive functioning relative to their Experientially Closed (EC) counterparts. The current study recruited an initial cohort of 220 well-educated and physically healthy adults aged 55-57 who volunteered to complete a total of six one-hour neurocognitive testing sessions (i.e.once every five years) over a 25-year period. Participants initially completed the NEO Personality Inventory. Cognitive testing included standardized measures of immediate and incidental memory as well as executive functioning. Results reflected that EO participants demonstrated better preservation of executive functioning, incidental memory, and immediate memory functions into late adulthood over their EC counterparts. Furthermore, although both personality groups eventually displayed cognitive decline into their late 70’s and 80’s, EC personalities displayed steeper rates of decline (i.e. slope gradients) at younger ages. T hese findings mirror prior longitudinal and cross-sectional studies which employed a variety of different cognitive measures across varying testing ages and lend support to the notion that personality differences may account for preserved differentiation and differential preservation of neurocognition among non-demented persons. These findings suggest that personality traits which promote active and novel sensory engagement may necessarily stimulate hippocampal neurogenesis in older adults through the formation of new neuronal pathways. Understanding and recognizing these individual differences in critical areas of cognitive processing may prove essential to improving the functional capacities and quality of life for older persons. 
 *Corresponding author David J Sperbeck, Ph.D. Fellow, National Academy of Neuropsychology, North Star Behavioral Health Hospital, 2530 Debarr Road, Anchorage,

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