http://www.medpagetoday.com/Cardiology/Dyslipidemia/39590?
Muscle pain has been associated with statin use, but new evidence suggests a link with skeletal adverse events as well, a propensity-matched study found.
The chances for any musculoskeletal disease diagnosis in those taking statins was significantly higher when compared with nonusers (odds ratio 1.19), reported Ishak Mansi, MD, of the VA North Texas Health Care System in Dallas, and colleagues online in JAMA Internal Medicine.
Also, statin users had a higher chance of being diagnosed with musculoskeletal adverse events in two out of three musculoskeletal subgroups based on ICD-9-CM codes:
- Dislocation/strain/sprain: OR 1.13 (95% CI 1.05-1.21)
- Musculoskeletal pain: OR 1.09 (95% CI 1.02-1.18)
However, in secondary analyses, the association of statins with joint disease or osteoarthritis was statistically significant.
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